Supelco^® Introduces Ascentis^® Express HILIC HPLC Columns for High-Speed and High-Efficiency Separations

Supelco^®, a division of Sigma-Aldrich, has expanded the Ascentis^® Express product line, a family of innovative high-purity liquid chromatography (HPLC) columns designed to provide the analysis speed and resolving power of sub-2-micron columns with a 50% reduction in backpressure. Ascentis Express HILIC can perform high-speed and high-resolution analyses on highly polar compounds.

"The retention of highly polar compounds such as metabolites has always been a challenge to reversed-phase HPLC. HILIC provides researchers with the ability to increase retention and selectivity for these important compounds. Ascentis Express HILIC enables high speed and high resolution in the analysis of highly polar compounds," said Wayne K. Way, Marketing Manager at Supelco in Bellefonte, PA. "Ascentis Express HILIC is useful in two-dimensional HPLC in which the second dimension provides orthoganality plus speed."

The enabling technology for Ascentis Express is the Fused-Core™ particle. These high-purity silica particles measure 2.7 microns overall with a 0.5 micron-thick porous shell. Relative to columns using conventional sub-2-micron particles, Ascentis Express columns generate comparable efficiencies but with half the backpressure.

Supelco's offering of HPLC products is one part of Sigma-Aldrich's technological and value-driven products that, combined with our services and support, provide complete analytical applications solutions.