Spinnovation Biologics Introduces New ICP-OES Elemental and Trace Metals Analysis for Cell Culture Media

4 Nov 2013
Sarah Thomas
Associate Editor

Product news

To offer a more complete analysis platform for cell culture, Spinnovation introduces new Elemental Analysis for cell culture media and raw materials. Elemental Analysis uses Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) to test samples for up to 30 elements and trace metals, at levels as low as parts per billion (ppb). With this service Spinnovation enables customers to characterize raw materials and monitor the elements critical to cells, for maximum cell culture production yield and optimal performance.

Elemental Analysis is a flexible custom analysis service, tailored to clients’ needs. Each customer may select the elements to be monitored in groups of up to 25. Elemental Analysis can be used to monitor both standard and trace level elements. Analysis is charged competitively on a pay-per-sample basis. Moreover, Spinnovation provides quick turnaround, with results typically delivered within 10 business days. This new offering complements the analysis packages already available at Spinnovation to develop troubleshoot and monitor bioprocess, including Spedia-NMR™, vitamin analysis and different raw material profiling assays.

Frederic Girard, CEO of Spinnovation Analytical, said, “Elemental Analysis adds to our advanced cell culture analysis offering, by allowing customers to quickly assess levels of elements vital to cell growth in cultures and to troubleshoot bioprocess performance variability. Together with Spedia-NMR™ for upstream processing and Spedia-Predict™ for achieving optimal and consistent bio-manufacturing performance, Elemental Analysis will allow us to meet all the needs of customers in the biologics field.”

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Atomic Absorption / Emission SpectroscopyAtomic absorption spectroscopy (AAS) and atomic emission spectroscopy (AES) — also called optical emission spectroscopy (OES) — are used to detect the elemental constituents in samples. Both techniques involve the atomization of a sample. Atomic absorption spectrometers may use a flame or furnace to create an atomic vapor of the sample before irradiation with spectral light. Optical emission spectrometers may use a flame, inductively coupled plasma (ICP), microwave plasma (MP) or spark arcs to atomize and excite the sample. At higher excitation energies, electrons can be emitted instead of photons, which can be useful for samples that can’t be atomized and for surface analysis. Explore electron spectroscopy equipment such as Auger spectrometers and photoelectron spectrometers for surface elemental analysis of samples. Find the best atomic absorption, photoelectron and optical emission spectrometers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Elemental AnalysisElemental analysis involves determining the elemental composition of a sample, often used in environmental, pharmaceutical, and material sciences. Techniques like ICP-MS, X-ray fluorescence, and atomic absorption spectroscopy allow precise quantification of elements such as metals and nonmetals in complex matrices. Browse our peer-reviewed product directory to find the best elemental analysis tools, compare products, check reviews, and get pricing directly from manufacturers.