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SCIEX Announces QTRAP 6500+ High-Throughput Mass Spectrometer at ASMS Conference, 2016

SCIEX

Enhanced, sensitivity and selectivity for small and large molecule quantitation

7 Jun 2016
Weylan Kiam-Laine
Microbiologist

Product news

SCIEX, a global leader in life science analytical technologies, has announced the introduction of the SCIEX QTRAP® 6500+ LC-MS/MS System, which further strengthens SCIEX’s high performance nominal mass spectrometry portfolio and continues the company’s legacy of improving technology and performance. The new system achieves improved sensitivity and selectivity over previous generation systems for small molecule quantitation and integrates with the BioBA Solution for large molecule quantitation, creating a powerful workflow system for biologics bioanalysis.

SCIEX continues to deliver exceptionally engineered, mass spectrometry-based technologies focused on customer needs. As customers are increasingly challenged to achieve lower levels of detection, the QTRAP 6500+ system offers new features that improve quantitation. Among the new features that improve small and large molecule quantitation are the multi-component IonDriveTM Technology with the new IonDrive High Energy Detector+ (HED), which pushes the boundaries of LC-MS/MS quantitation further than ever before. The increased detection area delivers sensitivity improvements in positive mode ionization and significant sensitivity improvements in negative mode ionization in the low mass region, depending on the analyte.

Mass spec users have also asked for more selectivity, as samples have become more and more complex, creating interferences that standard triple quad techniques, such as MRM, can no longer fully resolve. The QTRAP 6500+ system delivers enhanced selectivity, without compromising MRM sensitivity. The exclusive QTRAP scan function of MS3 (MS/MS/MS) adds an additional level of mass filtering, while the new SelexION®+ ion mobility technology provides an orthogonal separation prior to mass separation. The newly designed SelexION+ system has a 2x increase in ion transmission, and offers labs yet another tool for eliminating isobaric background interferences in complex assays, making quantitation in complex samples easier and less time consuming. Additionally, the unique scan functions offered by the SCIEX QTRAP system, including enhanced mass scans (EMS), enhanced resolution scans (ER), and enhanced product ion scans (EPI), deliver maximum flexibility and workflow options to enable new discoveries and more accurate identification for researchers whose work extends beyond quantitation alone.

“SCIEX is committed to delivering intelligent technological enhancements in support of our customers’ quantitation needs. The QTRAP 6500+ system is ultra-competitive in the areas of sensitivity and selectivity, not to mention dynamic range and stability,” said Chris Radloff, Global Vice President & General Manager of the LC-MS Business at SCIEX. “With the introduction of the QTRAP 6500+, SCIEX uniquely enables customers to expand their capabilities, even with the most challenging applications such as small molecule and complex large molecule analysis.”

The revolutionary sensitivity and selectivity delivered through these technologies are designed to see it all, from low mass to high mass compounds, in positive or negative polarity – in a single injection, with high sensitivity, reliability, and confidence, not only in small and large molecule bioanalysis, but also across applications such as comprehensive food residue monitoring, environmental analysis, lipid analysis, and forensic drug screening.

The SCIEX 6500+ system has already started shipping globally and has achieved a high customer adoption rate across applications.

For research use only. Not for use in diagnostic procedures.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.ASMSThe American Society for Mass Spectrometry (ASMS) is an organization dedicated to advancing the science and application of mass spectrometry. ASMS supports professionals through events, publications, and research initiatives, promoting innovation in areas like proteomics, metabolomics, and environmental analysis. Quantitative AnalysesQuantitative analyses involve measuring the amount or concentration of a substance in a sample using analytical techniques. These analyses are essential in fields like chemistry, biology, and environmental science. Explore quantitative analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.BiologicsBiologics are medical products derived from living organisms, including vaccines, gene therapies, and monoclonal antibodies. These treatments are key to modern healthcare, especially in oncology and autoimmune diseases. Explore biologics research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.MRMEnvironmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.Forensic InvestigationForensic investigation is a diverse collection of scientific techniques and methods for the identification and characterization of chemicals relating to crime scene investigations.

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