Phenomenex Introduces Onyx™ Semi-Prep (10mm ID) Monolithic HPLC Columns
9 Jan 2006Phenomenex Inc., Torrance, USA introduces Onyx C18 Semi-Prep 100 x 10mm, the newest addition to their portfolio of monolithic silica HPLC columns.
This format allows for flow rates from 5 to 35 mL/min with loading capacities typically between 10 and 20 mg. Onyx Semi-Prep is well suited for high-throughput purifications where impure samples and abusive ballistic gradients are encountered, such as in combinatorial library purifications. Also, due to the physics of the monolith, the DMSO solvent slug is well mixed improving purification results. In addition to high-throughput purification advantages Onyx has very low backpressures and excellent flow characteristics, which allows for injection of very dirty and/or viscous sample.
For more information on Onyx Monolithic Semi-Prep columns, please contact Phenomenex or visit the Article webpage.
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Onyx Monolithic LC Columns
Phenomenex IncAcheive Faster HPLCOnyx monolithic silica-based HPLC columns are designed for high-throughput analysis and the direct injection of dirty or viscous samples. Reduce run times with extremely high flow rates (up to 9 mL/min) "Dilute-and-Shoot” dirty biological samples Scalable from capillary to semi-prep column dimensions Onyx columns deliver high efficiency separations and can be coupled together in series to produce the extreme plate counts needed to separate very complex mixtures.Dilute & Shoot Complex mixtures coupled with dirty matrices, such as serum samples encountered in the pharmaceutical/biotechnology industry, are quite difficult and time-consuming to analyze. With Onyx however, you have the option to dilute-and-shoot your sample directly onto the column because it won't clog due to the macroporous system or cause high backpressures. Flow Rate Flexibility Another unique feature is the ability to use flow rate as parameter for optimizing separations. Onyx columns are responsive to changes in flow rate and can be changed mid run to reduce total run time when certain compounds elute much later. This type of flow rate flexibility gives many options for optimization.