Phenomenex Introduces Onyx™ 3mm ID Monolithic HPLC Columns
28 Nov 2006Phenomenex Inc., Torrance, USA introduces Onyx C18 100 x 3.0mm, the newest addition to their portfolio of monolithic silica HPLC columns. Onyx silica monolithic columns provide an excellent solution for applications where high throughput is essential.
The improved flow characteristics and high efficiency of Onyx allows high flow rates at low backpressures, resulting in dramatically reduced run times. The needs for slower flow rates & less solvent usage, but the ability to maintain high throughput, have led to the development of Onyx 3mm ID silica monolithic columns. The performance of the new Onyx 3mm ID C18 column is on par with that of the 4.6 mm ID column, however the narrower ID format enables the use of lower flow rates to get similar results to the 4.6mm while using less solvent. Due to the fact that methods using 3mm ID columns use less solvent it is much easier to couple the column to most mass spectrophotometers without requiring a post column split. The 3mm ID Onyx column makes it more convenient for scientists to adapt current particle-based methods onto Onyx silica monoliths, taking advantage of the increase in throughput & low backpressures that monoliths provide.
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Onyx Monolithic LC Columns
Phenomenex IncAcheive Faster HPLCOnyx monolithic silica-based HPLC columns are designed for high-throughput analysis and the direct injection of dirty or viscous samples. Reduce run times with extremely high flow rates (up to 9 mL/min) "Dilute-and-Shoot” dirty biological samples Scalable from capillary to semi-prep column dimensions Onyx columns deliver high efficiency separations and can be coupled together in series to produce the extreme plate counts needed to separate very complex mixtures.Dilute & Shoot Complex mixtures coupled with dirty matrices, such as serum samples encountered in the pharmaceutical/biotechnology industry, are quite difficult and time-consuming to analyze. With Onyx however, you have the option to dilute-and-shoot your sample directly onto the column because it won't clog due to the macroporous system or cause high backpressures. Flow Rate Flexibility Another unique feature is the ability to use flow rate as parameter for optimizing separations. Onyx columns are responsive to changes in flow rate and can be changed mid run to reduce total run time when certain compounds elute much later. This type of flow rate flexibility gives many options for optimization.