Phenomenex Expands Selectivity of Kinetex® Core-Shell Line with New Biphenyl Columns

6 Mar 2014
Sarah Thomas
Associate Editor

Product news

Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, announces new Kinetex Core-Shell Biphenyl HPLC/UHPLC columns, giving researchers the ideal orthogonal selectivity to traditional C18 phases. This new phase is excellent for a broad range of complex-mixture analyses in clinical research and forensic toxicology, food and environmental testing, and pharmaceutical, bioanalytical, and DMPK studies.

Kinetex Biphenyl columns deliver all the benefits inherent with Phenomenex’s Core-Shell Technology including better resolution, higher efficiency, sharper peaks, and greater sensitivity than traditional HPLC/UHPLC media. In addition to 100 percent aqueous stability and enhanced polar basic selectivity, the Kinetex 2.6 µm Biphenyl offers the greatest versatility for HPLC/UHPLC methods while the Kinetex 5 µm Biphenyl offers excellent HPLC performance at extremely low backpressures.

Orthogonal selectivity

“Analysts often attempt to expand the use of the traditional C18 columns with numerous additives and running condition alterations that can take a good amount of time to dial in correctly,” explains Simon Lomas, brand manager for Phenomenex. “Now they can supplement and transform reversed phase work with the orthogonal selectivity and performance that the Kinetex Biphenyl provides.”

Kinetex Biphenyl is initially available in 2.6µm and 5µm with a 1.7µm option expected next.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Forensic ToxicologyForensic toxicology is used to determine cause of death, drug use and contaminations. Toxicological evaluations are commonly used in analytical chemistry, clinical, life sciences and forensics.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.Environmental ContaminationContaminants in the environment are harmful chemicals that are present in the air, land and water. These include pesticides, pharmaceuticals, persistent organic pollutants (POPs) and many more.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.
Phenomenex Expands Selectivity of Kinetex® Core-Shell Line with New Biphenyl Columns