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PharmaNet Development Group to Demonstrate Comprehensive Capabilities at ASMS 2010

17 May 2010
Sarah Sarah
Marketing / Sales

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PharmaNet Development Group subsidiaries Taylor Technology and Anapharm will be showcasing a range of innovative bioanalysis solutions, including high resolution mass spectrometry applications. There will also be various poster sessions and short courses throughout the meeting.

Saturday May 22, 2010 - Sunday May 23, 2010
Richard LeLacheur, vice president, Taylor Technology, will teach his annual short course on High Resolution LC/MS for Structural Identification and Quantitation, where he will discuss the utility, advantages and limitations of conducting LC/MSn analysis using high resolution mass spectrometry.

Taylor Technology and Anapharm representatives will be further demonstrating their offerings in method development and validation and bioanalytical mass spectrometry via a series of presentations covering a wide range of scientific topics including:

Monday, May 24, 2010
Poster: How the Use of Incurred Samples is Important for the Validation of an Ultra Reproducible Assay for Exemestane, Presenter: Geneviéve Emond, Co-Authors: Nathalie Pelletier, Sylvain Lachance, Ann Levesque, Robert Massé

Poster: The Importance of Stopping Enzymatic Activity in Plasma for Accurate Analysis of Fluorouracil by LC/MS/MS, Presenter: Nadia Savard, Co-Authors: Louis-Charles Boisvert, Marie Josee Marcoux, Ann Levesque, Robert Massé

Poster: Use of Adducts for Quantitation of Compounds by Liquid Chromatography Coupled with Tandem Mass Spectrometry Detection, Presenter: Jérome Bergeron, Co-Authors: Sebastien Gagne, Isabelle M. Levesque, Marie-Josee Marcoux, Ann Levesque, Robert Massé

Tuesday, May 25, 2010
Presentation, 8:30 am: Beyond Successful ISR: Case by Case Investigations for Unmatched Reassay Results When ISR Passed, Presenter: Robert Massé, Vice President Bioanalysis, Anapharm will give a talk on incurred sample reassays (ISR), which currently is an important topic in the area of regulated bioanalysis, Co-Authors: Aimin Tan, Sylvain Lachance, Sofi Gagnon-Carignan, Ann Levesque

Poster: Chromatographic Separation of Enogenous Level of Hypoxanthine for the Analysis of Allopurinol and Oxypurinol in Human Plasma in Gout Patients, Presenter: Valerie Montmigny Co-Authors: Nadine Lafontaine, Nathalie Pelletier, Sylvain Lachance, Ann Lévesque, Robert Massé

Wednesday, May 26, 2010
Poster: Optimizing Tissue Analysis for LC-MS/MS in support of Drug Distribution Studies, Presenter: Nalini Anand, Co-Authors: Michael Koleto, Rohan Thakur, Tong Wu

Thursday, May 27, 2010
Poster: Sample Collection Stability Issue when Dealing with Highly Bounded to Erythrocytes Molecules, Presenter: Nadia Savard, Co-Authors: Marie-Jose Marcoux, Sylvain Lachance, Ann Lévesque, Robert Massé

Poster: Relative Instability of Deuterated Internal Standard under Different pH Conditions and According to Deuterium Atmos Location, Presenter: Guy Havard, Co-Authors: Marie-Ève Coulombe, Guy Havard, Sylvain Lachance, Ann Lévesque, Robert Massé

Poster: Simultaneous Quantitation of Free and Liposomal Drug Forms in Human Serum by Evaporation-Free Extraction, Presenter: Francois Viel, Co-Authors: Nuno Santos, Aimin Tan, Lise Laforest, Nadine Boudreau, Ann Lévesque, Adrien Musuku, Robert Massé

Poster: Robust and Ultra Sensitive Low Picograms Hormonal Contraceptive Determination by LCMSMS, Presenter: Guy Havard, Sylvain Lachance, Ann Lévesque, Robert Massé

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.

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