Pall Introduces 13 mm Acrodisc® MS Syringe Filter Certified for Low LCMS Extractables in Small Samples

28 Feb 2013
Sarah Thomas
Associate Editor

Product news

Pall Corporation has introduced a 13 mm Acrodisc® MS syringe filter certified for low extractables in high performance liquid chromatography/mass spectrometry (LCMS) applications. The new 13 mm size, which is designed specifically for small sample analysis using LCMS, complements Pall’s current Acrodisc MS syringe filter offering of a 25 mm filter. The 13 mm Acrodisc MS syringe filter improves the accuracy of testing, enhances LCMS performance, and extends the longevity of testing instrumentation.

The low extractable levels of the new 13 mm Acrodisc MS syringe filter minimize interference with the ionization process and reduce the need for retesting. This lowers costs while minimizing downtime due to unexpected contamination. To ensure high performance, product tubes are packaged individually so that filters not in use remain sealed and protected from external contamination.

Constructed with Pall’s new water wettable polytetrafluoroethylene (WWPTFE) membrane in a unique high density polyethylene housing, the Acrodisc MS syringe filter can be used with both organic and aqueous solvents. It offers excellent chemical resistance and good particulate retention with minimal protein adsorption. This protects instrument columns from particulate build-up and reduces the frequency and cost of replacement. It also enables more consistent LCMS testing performance.

“Pall’s 13 mm Acrodisc MS syringe filter is the newest innovation in our comprehensive line of syringe filters and is suitable for samples as small as 25 µL,” said Larry O’Connell, senior vice president, Pall Laboratory Products. “Our new size will continue to improve the accuracy, cost, and reliability of high performance LCMS testing. The applications for this advancement are extensive and growing rapidly as testing technology advances.”

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MS Syringe FiltersSyringe FiltersChromatography Method DevelopmentChromatography method development is the process of designing and optimizing chromatographic techniques to separate and analyze complex mixtures. This includes selecting appropriate stationary and mobile phases, determining flow rates, and optimizing detection methods. Successful method development is essential for high-quality results in fields like pharmaceuticals, food safety, and environmental analysis. Explore chromatography method development tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
Pall Introduces 13 mm Acrodisc® MS Syringe Filter Certified for Low LCMS Extractables in Small Samples