Oxford Gene Technology and Integrated Genomics to Develop a <i>Pichia pastoris</i> Gene Expression Microarray

7 Mar 2007

Product news

Oxford Gene Technology (OGT) and Integrated Genomics (IG) today announced the signing of a collaboration to develop and market a Pichia pastoris Gene Expression (GE) oligonucleotide microarray.

The collaboration gives OGT access to IG’s proprietary Pichia pastoris genomic sequence for the design and development of a high quality optimised 60 mer oligonucleotide microarray using the ink jet in-situ synthesis (IJISS) platform. OGT will market the array worldwide, and offer a sample analysis service at its Oxford laboratory.

Mr James Clough, Commercial Director at OGT said: “We are delighted to be working with Integrated Genomics. The combination of OGT’s oligonucleotide array expertise combined with Integrated Genomics sequence and detailed Pichia genome annotations will be a powerful molecular research tool for the Pichia community and add strength to our growing portfolio.”

Dr Theresa Walunas, Vice President of Integrated Genomics added: “OGT’s IJISS technology provides an important new capability to the Pichia research community. Microarrays will allow researchers to understand how Pichia’s gene expression changes in response to genetic modifications.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.