Nexera MX Accelerates Workflow and Improves Analytical Efficiency

In the year of its 140th anniversary, Shimadzu, one of the world leaders in analytical in­strumentation, has released the new Nexera MX ultra-fast multianalyte LC-MS system. It offers up to double the sample processing capability of the conventional approach. The Nexera MX features two analytical flow lines in a single LC-MS system. This setup max­imizes operating efficiency by alternating between the two lines for injecting of sam­ples. Capable of rapidly processing large num­bers of samples, the Nexera MX will help to improve the workflow of customers.

High-speed LC-MS meets unique autosampler

The processing sequence in LC-MS-based analysis involves sample aspiration and injec­tion, target component elution and detection, analytical column rinsing and equili­bra­tion. In this process, the mass spectrometer must wait in standby mode except dur­ing data acquisition. Demands have therefore increased for LC-MS systems that offer maxi­mum uptime while minimizing the time required for steps other than data acquisi­tion.

The Nexera MX satisfies such needs by combining the superior high-speed analytical performance of Shimadzu LC-MS systems with the SIL-30ACMP autosampler de­signed with a unique flow line structure and high-speed sample injection capability. This com­bination dramatically improves analytical efficiency and maintains ease-of-opera­tion.

Features:

Flow line design optimized for rapid analysis of large numbers of samples

The Nexera MX features two independent analytical flow lines: one line can be used to perform LC-MS analysis while the other line is busy equilibrating the analytical column and preparing to inject the next sample.

This configuration maximizes the efficiency of LC-MS data acquisition.

The system also includes the high-speed SIL-30ACMP autosampler, which is capable of injecting samples in just seven seconds. This eliminates the previous bottleneck involved in processing large numbers of samples. The autosampler also reduces carryover to nearly zero, so that the next sample can be aspirated and injected without rinsing. Consequently, it enables continu­ous analysis at a cycle time of 20 seconds per sample.

User interface significantly improves analytical workflow

Each operating button in MX Solution, the dedicated software for the Nexera MX system, is arranged in a visual, easy-to-understand layout. This enables reliable performance of the entire series of analytical operations, from system startup, registering and analyzing of samples to shut down. This user-friendly interface ensures that even those with little experience in use of analytical instruments can operate the system intuitively, smoothly, and with minimal human error.

Easy to analyze massive amounts of LC-MS data

The Nexera MX system also includes LabSolutions Insight software, pro­viding assistance with quantitative analysis of large volumes of data. The soft­ware not only helps to extract measurement results quickly for target com­pounds from the massive amounts of LC-MS data generated, but can also display color-coded quantitative results automatically in five levels for each concentration range. This allows quick screening of samples for the presence of target compounds, abnormal values or other evaluations.