Nexcelom Bioscience Extends Line of Automated cell Counting Instruments with Launch of High Throughput Model

23 Dec 2008
Samantha Rosoman
Campaign Coordinator

Product news

Nexcelom Bioscience LLC, provider of innovative automated cell counting products for cell biology, cancer research and drug discovery, today announced it has extended its product line with the launch of the Cellometer Auto M4, high throughput automated cell counter. The Auto M4 incorporates all the unique benefits of the proven Cellometer platform, and broadens its capabilities by allowing users to count entire panels of cell lines with increased walk-away and data handling capabilities.

“Cellometer cell counters typically take less than 30 seconds to count one sample, but instead of waiting for each sample to be counted and analyzed before loading the next, the Auto M4 allows users to acquire all cell images first, and then count the entire panel of cells without being present at the instrument.” said Craig Weiss, Vice President of Marketing at Nexcelom Bioscience. “The cell images acquired in the lab can be analyzed and counted on separate computers on the network, eliminating the need to return to the bench to analyze results thus freeing up time at the bench by 50% or more.”

Cellometer Auto M4 also features enhanced optics capabilities that doubles the measurement area and increases statistical accuracy.

“The Cellometer Auto M4 was developed in response to users who employ cell lines for drug screening. They need to accurately analyze panels of different cell lines in a more efficient manner than one sample at a time.” Craig concluded, “Other features such as automatic sample id generation and automated data organization increases efficiency, reduces the chance of errors, and offers higher counting throughput for the lab.”

Like other Cellometer instruments, the Auto M4 has a very compact footprint of only 3.5 by 4 inches, saving lab bench space. Auto M4 software incorporates the intuitive and powerful Cellometer cell counting algorithm for accurately counting cells, determining viability, measuring cell sizes, and more.

Unlike other high throughput automated counters, the Auto M4 features economical, easy-to-load disposable counting chambers which require only 20µl of sample. Disposable counting chambers also eliminate the need for on-board liquid handling, washing steps between samples and the potential for clogging and cross-contamination.

The launch of Cellometer Auto M4 reflects Nexcelom Bioscience’s continued dedication to innovating rapidly in response to customers’ needs. Since Cellometer was launched in 2006, scientists in the biomedical and life science fields around the world have been using the novel cell counting solution in their daily research and development activities.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Robotic InstrumentsRobotic instruments can be used for high-throughput automation of many lab processes. Such processes use instruments for assays like cell based assays and ELISA, for sample preparation like shakers, centrifuges and incubators, and for analysis such as sequencing and western blot analyzers. Useful features of robotic instruments include speed, reproducibility, barcode readers, software and automation.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.
Nexcelom Bioscience Extends Line of Automated cell Counting Instruments with Launch of High Throughput Model