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New THAP11 Antibody from Novus Biologicals

Novus Biologicals, LLC
9 Dec 2010
Kerry Parker
CEO

Product news

Novus Biologicals just announced a new THAP11 antibody (catalog # NBP1-49463). THAP11 antibodies, also known as Thanatos-associated protein 11 antibodies, are useful for cancer studies and stem cell research. THAP-11 is a regulator of embryonic stem cells and is in the same field as Oct4, Sox2 and Nanog.

This THAP-11 antibody has been validated for use in immunohistochemistry, Western blot, and immunocytochemistry/immunofluorescence. The immunogen to which Novus' new anti-THAP11 antibody was made is a partial recombinant human THAP11 protein expressed in E. coli. This rabbit polyclonal antibody to THAP11 is provided as whole antisera and is available in two sizes (100uL and 25uL).

THAP11 is a member of the thanatos-associated proteins (THAP) family and is the most recently characterized member of the THAP family. In a study published in Cell Death & Differentiation, researchers showed that THAP11 is frequently downregulated in several human tumor tissues and is able to suppress transcription of c-Myc (PMID: 19008924).

Novus Biologicals provides THAP11-related products, such as c-Myc antibodies, OCT4 antibodies, and Nanog antibodies, as well as other THAP-11 antibodies. For more information on this new THAP11 antibody or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via the 'request info' button above right.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Western BlottingWestern blotting equipment is used to transfer and identify specific proteins within a sample, reveal protein modifications, as well as give a semi-quantitative estimation of their concentration. Western blotting equipment includes all apparatus necessary to transfer proteins from gel to membrane and subsequent processing steps. Protein transfer can be performed by electroblotting with wet, semi-dry and dry transfer systems onto nitrocellulose and PVDF membranes. Blocking, washing and labeling of membranes follows, involving buffers, blocking reagents, blotting / incubation trays, labeling reagents, immunoblotting assays, antibodies and conjugates. Automated equipment for these steps is available to accelerate your lab workflow. Finally, detection and imaging of proteins can be conducted using gel documentation and imaging systems. Find the best western blotting equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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New THAP11 Antibody from Novus Biologicals