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New Multiplexed Secreted Protein Assays at the Pace and Price of Screening

Sartorius Group
6 Jan 2014
Kerry Parker
CEO

Product news

Visit IntelliCyt Corporation at booth 1341 and learn how to revolutionize your phenotypic screening with the iQue™ Screener platform. High capacity with high content data on cells, beads, microbes and mixtures in suspension formats is now a reality for your drug discovery workflow.

NEW MultiCyt™ QBeads PlexScreen on iQue™ Screener

Overcome the limitations of current methods to capture multiplexed secreted proteins in screening applications. IntelliCyt has created the most rapid, simple, and affordable method in the industry.

  • Easy - No wash screening formats reduce the need for complex separation steps. Pre-configured analysis templates take the guesswork out of assay development.
  • Fast - Generate multiplexed bead data from a 384-well plate in < 30 minutes. Quickly create custom screening profiles from 40+ analytes using their intuitive Assay Builder web application.
  • Economical - IntelliCyt’s unique technology enables the miniaturization of assay volumes, dramatically reducing reagent and precious sample usage over the course of your screening campaigns.

NEW Capabilities for the iQue™ Screener

Nominated for 2013 Drug Discovery Product of the Year, the iQue™ Screener keeps getting better and better. Higher density plate formats and new multiplexed data analysis tools are some of the new features you can discover at booth 1341.

SLAS2014 Tutorial: The New Role of Phenotypic Screening using Suspended Assay Formats Tuesday, January 21, 12:30pm-1:45pm, San Diego Convention Center, Room 26B

IntelliCyt’s iQue™ Screener adds a powerful new tool for suspension formats to phenotypic and target-based screening. Critical biologies can now be addressed with the capacity and content needed to make drug discovery decisions at the right time. New applications for evaluating compound effects in primary immune system cells will be discussed and several IntelliCyt users will present case studies. Space is limited.

Register Now» IntelliCyt: Screening Solutions for Life @ SLAS Booth 1341. See you there!

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Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Robotic WorkstationsRobotic workstations are automated platforms enabling the user to perform high-throughput, multi-application processes, from sample preparation tasks such as PCR set-up, DNA purification and NGS library preparation, to integrated sample prep and analysis workstations. Automation makes processes consistent, fast, precise and fully walk-away. Find the best robotic workstations in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.Phenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.

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New Multiplexed Secreted Protein Assays at the Pace and Price of Screening