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New Automated Microscopy Platform from ZEISS offers High Flexibility and Throughput

ZEISS Research Microscopy Solutions

ZEISS introduce the Celldiscoverer 7 inverted microscope for live cell imaging

9 Dec 2016
Weylan Kiam-Laine
Microbiologist

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ZEISS introduces a new system for automated microscopy in life sciences research. ZEISS Celldiscoverer 7 combines the user-friendly automation features of a boxed microscope with the image quality and flexibility of a classic inverted research microscope. Scientists acquire better data in shorter times with 2D or 3D cell cultures, tissue sections or small model organisms.

In contrast to other boxed microscopes with limited flexibility, ZEISS Celldiscoverer 7 can be adapted to a whole range of tasks and applications. The system comes with various incubation and detection options and can be tailored to the individual needs of research labs. Users can choose from a selected range of microscope cameras for even the most demanding live cell experiments and rapid time-lapse recordings. In particular, the new ZEISS Axiocam 512 mono microscope camera with highest 12 MP resolution and a large field of view allows fluorescence screening applications with high throughput.

The new optical design of ZEISS Celldiscoverer 7 together with advanced automatic calibration routines helps researchers to achieve reproducible high quality data even from complex long-term, time-lapse imaging experiments. A new hardware-based autofocus not only finds and keeps the focus automatically, but also detects the thickness and optical properties of the sample carrier. This information is then used to adapt the unique ZEISS Autocorr objectives to deliver the best image quality possible.

ZEISS Celldiscoverer 7 is controlled by ZEN imaging software that provides additional key features for the automated microscope system. The dedicated software package from ZEISS for example calculates the maximal scanning area for any sample carrier automatically and actively protects the objective from collisions with your sample vessel or other hardware components. ZEN 2.3 offers convenient experiment setup with user-friendly automation wizards, large-data acquisition, and data processing in 2D and 3D. The newly developed optics of ZEISS Celldiscoverer 7 in combination with rapid GPU-based deconvolution algorithms allow scientists to extract a maximum of information from their samples, artifact-free and in the shortest time possible. As ZEN supports open interfaces and scripting, ZEISS Celldiscoverer 7 can be integrated in virtually every lab workflow. Experiment data is easily exported to a multitude of file formats and third-party image analysis software.

ZEISS Celldiscoverer 7 is the new reliable research platform that offers a unique combination of automation features in life science research. The system will be on display at the upcoming Neuroscience and ASCB annual meetings and is available for live demonstrations worldwide.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Live Cell ImagingLive cell imaging is the study of living cells using microscopes and high-content imaging systems. This technique provides in-depth insight into fast and complex biological processes, by allowing dynamic imaging of living cells instead of acquiring an individual image at a single point in time.MicroscopyMicroscopy is a technique used to observe small objects in detail, from cells to materials, using light or electron microscopes. It enables researchers to examine structures with high resolution, aiding in fields such as biology, medicine, and materials science. With advanced microscopy techniques, scientists can gain insights into cellular processes, tissue structures, and material properties. Explore the best microscopy solutions in our peer-reviewed product directory, compare products, read customer reviews, and get pricing directly from manufacturers.

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