New AC Extraction Plate™ from Tecan Provides a Unique Sample Preparation Tool for LC-MS

30 Oct 2013
Sarah Thomas
Associate Editor

Tecan’s newly launched AC Extraction Plate is a revolutionary, automation-friendly solution designed to streamline sample preparation for LC-MS analysis of small molecules. The plate, which is based on proprietary TICE™ (Tecan Immobilized Coating Extraction) technology, reduces the sample preparation process to a convenient ‘pipette and shake’ routine.

The AC Extraction Plate is a 96-position, deep-well microplate, with the inner surface of each well coated with a highly controlled layer of TICE material. This coating efficiently extracts low molecular weight analytes – such as vitamin D and testosterone – from aqueous solutions, eliminating the need for the laborious and time-consuming filtration, centrifugation and evaporation steps that are often integral to other methods. Unlike many of these techniques, sample preparation with the AC Extraction Plate can also be easily automated, providing a rapid, walkaway solution for the extraction of small molecules from biological fluids for LC-MS analysis.

AC Extraction Plate™

Tecan

The Tecan AC Extraction Plate* with TICE™ (Tecan Immobilized Coating Extraction) technology revolutionizes your sample preparation routine. The AC Extraction Plate is a 96-well, deep-well microplate, with each well having a proprietary TICE™ coating. TICE is a material with distinct absorptive properties, and this coating efficiently extracts specific small molecule analytes from aqueous solutions, releasing them when in contact with a suitable organic solvent. A simple pipette and shake sequence, with no filtration, centrifugation or solvent evaporation, is all that is required. The AC Extraction Plate is easily integrated into automated processes, making it a perfect match with Tecan’s Freedom EVO® liquid handling platform. AC Extraction Plate™ Features: Cost-effective – Simple pipette and shake workflow, without labor intensive centrifugation, filtration and solvent evaporation steps. Convenient and fast – Just unpack and start, no conditioning or other preparations needed. Highly reproducible – Pipette and shake routines are easily standardized and automated on a liquid handling platform, eliminating random errors and increasing consistency of results. * For research use only – not for clinical diagnostic applications

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New AC Extraction Plate™ from Tecan Provides a Unique Sample Preparation Tool for LC-MS