Near-IR Variable Path Transmission Sampling System Facilitates Rapid Application Development for Process Analytical Technology

24 Feb 2010
Sarah Sarah
Marketing / Sales

Product news

Axiom Analytical, Inc. has announced its fiber-optic coupled FST-600N Series Near-Infrared Transmission Sampling Systems. Available in both manual and auto-sampling versions, the new spectroscopic sampling systems provide the ability to analyze pharmaceutical and chemical samples over pathlengths ranging from zero to 5 mm.

The operation of the FST-600 is based on the use of a moveable fiber-optic probe. This is mounted on a rack and pinion stage with an electronic path length readout. Samples are contained in cuvettes or plastic bags. Both heated and multisampling stages are available.

The auto-sampling version of the FST-600 features computer control of path length and sample sequencing. This allows the system to be programmed to sequentially analyze multiple samples either at a fixed path length or a series of path length.

The Company anticipates that the FST-600 will find application in fields such as chemical and pharmaceutical development as well in process analytical technology (PAT) modeling and scale-up. Methods developed using the FST-600 can be applied on-line in full-scale chemical process analysis in batch reaction vessels or continuous process by using the Company’s robust FPT Series fiber-optic near-IR process transmission probes and spectroscopic flow cells.

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Near Infrared SpectroscopyNear-infrared (NIR) spectroscopy measures the interaction of near-infrared light with a sample, including transmission, reflectance and absorbance, facilitating the identification of analytes. Measurements can be conducted using a Fourier-transform near infrared (FT-NIR) spectrometer, while there are also UV-Vis- NIR spectrophotometers that measure a broader spectrum of wavelengths. Find the best NIR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.
Near-IR Variable Path Transmission Sampling System Facilitates Rapid Application Development for Process Analytical Technology