Labcyte Receives 1st Patent in China for Droplet Ejection Technology and Liquid Transfer

27 Sept 2010

Sarah Sarah

Marketing / Sales

Product news

Labcyte announces the grant of its first patent in China. Patent CN 101035681B describes how acoustic energy is used to assess the characteristics of any fluid in real time to optimize its transfer. The Labcyte acoustic droplet ejection technology offers touchless transfer of a wide variety of liquids, with major benefits in life science applications including drug discovery, genomics, proteomics and diagnostics.

“The life sciences industry in China is the world’s highest growth market and the pharmaceutical and biotech markets are expected to be the 3rd largest market, after the USA and EU, in the world by 2013 at $73 billion,” said Sanger Chang, General Manager of Tekon Biotech, the Labcyte distributor in China. “Labcyte products have already been successfully adopted by some of the largest pharmaceutical and CRO companies in China as well as by all ten of the top ten pharmaceutical companies globally. As discovery platforms are standardized and adopted globally we see significant opportunity for the Labcyte products in China.”

“This new feature—already incorporated in our products—allows customers to transfer liquids for a wide range of applications including siRNA screening, qPCR, genotyping and total assay assembly for drug discovery,” said Rich Ellson, Labcyte CTO. “Customers have chosen Echo liquid handlers because they provide better precision and accuracy, reduce operating costs and eliminate cross-contamination. The technology described in the patent allows users to transfer many different fluids with factory-installed calibrations that require no user customization. The built-in intelligence of the Echo platform automatically optimizes fluid transfer well by well.”

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Echo® 555 liquid handler - the world's fastest acoustic dispensing platform for life science applications. The Echo® 555 liquid handler is the world’s fastest acoustic liquid handling platform for life science applications. Laboratories that demand very high throughput rely upon the Echo 555 liquid handler for round-the-clock trouble-free operation to enable the fastest discovery.The Echo 555 doubles the throughput of the Echo 550 and provides transfers from as many as 660,000 wells per day. Like the Echo 520 and Echo 550 liquid handlers, the Echo 555 uses "touchless" ADE transfer technology. ADE uses sound energy to transfer 2.5 nL droplets from Echo-qualified 384- and 1536-well source plates into 96-, 384-, 1536- and 3456-well destination plates.This unique touchless technology eliminates consumable tip costs, washing, and cross-contamination. Unsurpassed volumetric precision (≤ 8% CV) and accuracy (≤ 10% CV) ensure superior results. Independent studies have shown that Echo liquid handlers eliminate false negatives due to sample loss on tip surfaces in low-concentration transfers. Like the Echo 550 liquid handler, the Echo 555 liquid handler reports both fluid volume and DMSO hydration.Echo® 555 Liquid Handler Features: Tipless transfer, resulting in dramatic cost savings Accurate, precise movement of nanoliter-scale quantities, enabling assay miniaturization and further reducing costs Elimination of cross-contamination, carryover or leachates Better results through direct dilution of compounds, an improvement over serial dilution methods Improved information about sample integrity and improved transfer quality through measurement of DMSO hydration level Applications: Compound management Compound screening siRNA screening Biochemical assays Cell-based assays PCR Genotyping Gene expression
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Echo® 650 Acoustic Liquid Handler
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Enables assay miniaturization in a broad range of applications. Transfer from 384-well and 1536-well microplates. Accurate, precise, contact-free acoustic transfer in volumes as low as 2.5 nL Transfer from Echo Qualified sample tubes* and microplates.
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Echo® 520 Liquid Handler
Beckman Coulter Life Sciences
Imagine preparing assay plates for siRNA screening, compound screening with biochemical and cell-based assays, PCR reactions and more all on a single liquid handling platform, with no tips and no cross-contamination. Labcyte has developed new acoustic droplet ejection (ADE) parameters that deliver built-in intelligence to enable users to transfer many different fluid types from a single instrument. All Echo systems come pre-calibrated so that you can switch among different fluid types with just a click of the mouse. No further adjustment is required for you to be productive immediately. These developments combine the latest discoveries in wavelength, power and timing requirements for ADE with real-time fluid measurement at multiple points during a run. The resulting algorithms solve some of the most significant liquid handling challenges with volatile, low-surface tension and/or meniscus-shifting fluids. Volumetric accuracy and precision for all fluids tested so far—including buffers, nucleic acid and protein solutions, surfactants, serum and cell culture media—are comparable to established performance with DMSO. The Echo® 520 liquid handler delivers the same superior precision and accuracy as the award-winning 550 and 555 models, for laboratories with lower throughput needs. Like the Echo 550 and Echo 555 liquid handlers, the Echo 520 uses "touchless" ADE transfer technology. ADE uses sound energy to transfer 2.5 nL droplets from Echo-qualified 384- and 1536-well source plates into 96-, 384-, 1536- and 3456-well destination plates. This unique touchless technology eliminates consumable tip costs, washing, and cross-contamination. Unsurpassed volumetric precision (≤ 8% CV) and accuracy (≤ 10% CV) ensure superior results. Independent studies have shown that Echo liquid handlers eliminate false negatives due to sample loss on tip surfaces in low-concentration transfers. The Echo 520 liquid handler reports source well volume, but does not report DMSO hydration values. Applications: • Compound management • Compound screening • siRNA screening • Biochemical assays • Cell-based assays • PCR • Genotyping • Gene expression
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Echo® 500 Series Liquid Handlers
The Echo® liquid handler revolutionizes liquid handling with acoustic energy. Sound waves eject precisely sized droplets from a source onto a microplate, slide or other surface suspended above the source. This product does not use tips, pin tools or nozzles—completely eliminating contact between the instrument and the liquid. The Echo liquid handler provides powerful benefits: Tipless transfer, resulting in dramatic cost savings Improved information about sample integrity and improved transfer quality through measurement of DMSO hydration level Elimination of the need for calibration through Dynamic Fluid Analysis™ technology, a patented Labcyte process Elimination of cross-contamination, carryover or leachates through non-contact transfer Accurate, precise movement of nanoliter-scale quantities, enabling assay miniaturization and further reducing costs Better results through direct dilution of compounds, an improvement over serial dilution methods Greatly simplified assay development and dilution processes through the flexibility to transfer any volume of liquid from any well to any other well
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Genome AnalysisProteomicsAutomated Liquid Handling

Echo® 520 Liquid Handler

Beckman Coulter Life Sciences

Imagine preparing assay plates for siRNA screening, compound screening with biochemical and cell-based assays, PCR reactions and more all on a single liquid handling platform, with no tips and no cross-contamination. Labcyte has developed new acoustic droplet ejection (ADE) parameters that deliver built-in intelligence to enable users to transfer many different fluid types from a single instrument. All Echo systems come pre-calibrated so that you can switch among different fluid types with just a click of the mouse. No further adjustment is required for you to be productive immediately. These developments combine the latest discoveries in wavelength, power and timing requirements for ADE with real-time fluid measurement at multiple points during a run. The resulting algorithms solve some of the most significant liquid handling challenges with volatile, low-surface tension and/or meniscus-shifting fluids. Volumetric accuracy and precision for all fluids tested so far—including buffers, nucleic acid and protein solutions, surfactants, serum and cell culture media—are comparable to established performance with DMSO. The Echo® 520 liquid handler delivers the same superior precision and accuracy as the award-winning 550 and 555 models, for laboratories with lower throughput needs. Like the Echo 550 and Echo 555 liquid handlers, the Echo 520 uses "touchless" ADE transfer technology. ADE uses sound energy to transfer 2.5 nL droplets from Echo-qualified 384- and 1536-well source plates into 96-, 384-, 1536- and 3456-well destination plates. This unique touchless technology eliminates consumable tip costs, washing, and cross-contamination. Unsurpassed volumetric precision (≤ 8% CV) and accuracy (≤ 10% CV) ensure superior results. Independent studies have shown that Echo liquid handlers eliminate false negatives due to sample loss on tip surfaces in low-concentration transfers. The Echo 520 liquid handler reports source well volume, but does not report DMSO hydration values. Applications: • Compound management • Compound screening • siRNA screening • Biochemical assays • Cell-based assays • PCR • Genotyping • Gene expression

(2)

Labcyte Receives 1st Patent in China for Droplet Ejection Technology and Liquid Transfer

Product news

Related products

Echo® 555 Liquid Handler

Echo® 650 Acoustic Liquid Handler

Echo® 520 Liquid Handler

Echo® 500 Series Liquid Handlers

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