IntelliCyt Corp Introduces New High Throughput Flow Cytometry Screening System

13 May 2010
Sarah Sarah
Marketing / Sales

Product news

IntelliCyt Corp. introduces new high throughput flow cytometry – HTFC™ Screening System at the 25th International Society for Advancement of Cytometry in Seattle.

Designed to enable large scale, high throughput, high content screening, IntelliCyt’s new HTFC Screening System takes a revolutionary approach to cell-based screening by integrating the company’s proprietary HyperCyt® technology and flow cytometry – the most sensitive technology for measuring fluorescent markers on cells in suspension – with HyperCytPRO, IntelliCyt’s advanced server-based informatics platform. The result is a powerful yet simple screening system that enables researchers to cost effectively perform broader experiments with more controls and replicates, screen more compounds, and analyze data in ways never before possible with conventional flow cytometry.

“The HTFC Screening System represents a significant breakthrough in high content screening because it broadens the types of cells and multiplexed assays that can be used for testing compounds in drug discovery research,” said Terry Dunlay, IntelliCyt president and CEO. “By coupling our high-throughput sampler with the large dynamic range and multiplexing capability of flow cytometry-based detectors, the HTFC Screening System provides scientists with powerful advantages over other currently available technologies.”

Using the HTFC Screening System, researchers can analyze multiparameter cell populations or multiplexed bead suspensions in 96- and 384-well microplates at rates up to 40 wells per minute, capturing data on thousands of cells per second. Because the HTFC Screening system can accommodate very small specimens, sample and reagent requirements are reduced by 50 to 90 percent, resulting in significant cost savings. The heightened sensitivity and multicolor capabilities of the flow cytometer detection system also enable additional applications, including antibody screening, cytotoxicity studies and biomarker analysis.

“We are grateful to many of our early customers, who have been using earlier versions of our HyperCyt Systems at major pharmaceutical companies, biotechnology companies, and leading academic research organizations. Their feedback led to many of the new powerful and user-friendly features in the HTFC Screening System,” said Dunlay.

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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Content ScreeningHigh-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
IntelliCyt Corp Introduces New High Throughput Flow Cytometry Screening System