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Improving Periprosthetic Infection Diagnosis with New microDTTect Solution

Heraeus Medical
16 Apr 2018
Han Yin
Administrator / Office Personnel

Product news

With the European launch of microDTTect, Heraeus is now offering a novel solution for the diagnosis of periprosthetic infections. For the first time, orthopedists and microbiology labs can use a closed system to allow the contamination-free removal of bacterial biofilms on tissue and sample materials for further analysis.

In the lab, microDTTect has demonstrated enhanced sensitivity and specificity in microbial detection of up to 94%, thereby significantly facilitating the correct diagnosis and treatment of biofilm-associated infections.

Identification of pathogens is key for the right treatment

Biofilm-associated pathogens are a major challenge in orthopedic revisions as their identification is difficult. This impedes the discrimination of septic and aseptic loosening and the correct patient treatment. For the hospital, this challenge poses a high risk of medical complications and additional costs. Heraeus Medical now offers microDTTect as a novel solution to dissolve the biofilm for the release of pathogens. The risk of contamination during handling, transport and processing of the samples is reduced due to easy filling and airtight sealing of the system. These advantages facilitate the correct diagnosis of pathogens: patients benefit from a speedy recovery and targeted antibiotic treatment, while hospitals can free up personnel and financial resources.

Convenient solution for operating theatres and laboratories

With microDTTect, Heraeus Medical introduces an easy-to-use solution that can be seamlessly integrated into the workflow in operating theatres and microbiology labs. microDTTect consists of a sterile, sealable plastic pouch, in which sample materials removed during surgery (implants, biopsies) are placed. Following proper sealing of the pouch, the samples are protected from contamination. Dithiothreitol (DTT) is added via a valve system and dissolves the polysaccharide matrix of the biofilm to release the bacteria without killing them. This step allows the cultivation of the pathogens for identification and detection of antibiotic resistance.

MicroDTTect is available in three sizes, all with or without equipment for direct injection into a blood culture bottle.

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MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Point of Care SolutionsPoint of care solutions provide medical diagnostics and treatments at or near the site of patient care. These technologies offer rapid results, helping healthcare providers make quick decisions. From glucose monitors to molecular diagnostics, point of care solutions are transforming healthcare delivery by reducing wait times and improving patient outcomes. Explore the best point of care products in our peer-reviewed product directory, compare options, check reviews, and get pricing directly from manufacturers.Contamination PreventionContamination prevention aims to control and minimize the risk of contamination during experiments. Biological safety cabinets and sterilization equipment are examples of technologies used to prevent contamination.Bacterial DetectionBacterial detection uses methods such as cell culture, microscopy, and biochemical assays to identify harmful or beneficial bacteria based on their morphological and metabolic charactersistics. These techniques support disease diagnostics, food safety, and microbial research. Explore bacterial detection systems, kits, and consumables in our directory to compare products and read reviews.Biofilm

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Improving Periprosthetic Infection Diagnosis with New microDTTect Solution