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Improving Drug Therapies a Single Cell at a Time using Single Cell ICP-MS: Free Webinar

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Register for the free webinar on June 12, 2017 at 4pm BST/5pm CEST/11am EDT/8am PDT

16 May 2017
Sarah Thomas
Associate Editor

Expert insights

On June 12, join us for this SelectScience® webinar to learn how single-cell inductively coupled plasma mass spectrometry (ICP-MS) is advancing the analysis of cancer drug therapies.

It is estimated that in 2017, over 1.6 million new cancer cases will be diagnosed. Cisplatin and other platinum-based analogs, remain a mainstay in the clinic treating a wide range of tumors including ovarian, lung, testicular, bladder, as well as others. Frequently the patient initially responds to chemotherapy but when the tumor returns, patients are resistant to further platinum-based chemotherapy. With new research, scientists are taking a cellular step closer to understanding how cisplatin chemotherapy, and other metal-based cancer drugs, can be developed to improve their success rates.

In this webinar, Lauren Amable, Ph.D., Staff Scientist, National Institute on Minority Health and Health Disparities (NIMHD) and Chady Stephan, Ph.D., Product Manager for Customer Solutions, PerkinElmer, Inc. will discuss the use of single cell ICP-MS in enabling researchers to see how effective a cancer drug is performing for each and every cell in a tumor.

Watch this webinar to learn:

  • Single cell ICP-MS analysis methodology to study metal uptake at a single cell level
  • Quantifying single cell uptake with cisplatin
  • Novel targets for increasing cisplatin uptake
  • Overcoming current challenges with drug uptake analysis

There will also be a question and answer session at the end of the webinar for you to ask any questions you may have.

Register now for the live event on June 12, 2017 at 4pm BST/5pm CEST/11am EDT/8am PDT.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Drug TestingIt is essential to test the efficacy and toxicity of drugs at every stage of their development to ensure that a pharmaceutical product is fit for purpose and safe for use before reaching the stage of mass production and distribution.Single Cell AnalysisSingle-cell analysis involves studying individual cells to gain insights into their behavior, gene expression, and function. This approach is valuable in cancer research, stem cell biology, and immunology. Explore single-cell analysis products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ICP-MSInductively Coupled Plasma Mass Spectrometry (ICP-MS) is a powerful analytical technique used to determine the concentrations of elements and their isotopes in a variety of samples, including water, soil, and biological tissues. It involves ionizing elements in the samples with extremely high-temperature Argon (Ar) plasma and then using a mass spectrometer to measure the number of ions based on their mass-to-charge ratio (m/z). Explore ICP-MS systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.

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