Human LDH Isoenzymes Available from Lee Biosolutions

14 Jun 2007

Product news

Lee Biosolutions has announced the production and availability of five Human Lactate Dehydrogenase Isoenzymes – LDH-1, LDH-2, LDH-3, LDH-4 and LDH-5 – for purchase. Refer to Item No. 355-15 for the most popular LDH Isoenzyme product from the human heart, LDH-1.

Human lactate dehydrogenase isoenzymes are primarily used by cells in specific tissue. LDH, also known as lactic dehydrogenase, is responsible for converting muscle lactic acid into pyruvic acid, an essential step in producing cellular energy.

When injury occurs, cells containing specific LDH isoenzymes are released in the bloodstream. Analyzing specific LDH isoenzyme ratios helps identify certain patterns in order to aid in the diagnosis of disease such as heart attack, lung injury, lung disease, liver or muscle disease, advanced cancers and autoimmune diseases.

According to Lee Biosolutions President Burton Lee, the company keeps close tabs on the clinical research community in an effort to stay ahead of widespread demands for products like Human Lactate Dehydrogenase Isoenzymes.

“Lee Biosolutions has developed a reputation for high-quality biomarker production,” said Lee. “We isolate LDH isoenzymes from the human heart, human red blood cells and the human liver. As a manufacturer of high purity human enzymes, we are able to custom fill orders and we will, likewise, place the protein in the buffer of your choice, if required.”

Burton also indicated Lee Biosolutions focuses on providing consistently pure products to the clinical research community. “We continue to expand our product line based on developing trends in the industry,” he added.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.
Human LDH Isoenzymes Available from Lee Biosolutions