Histology Image Analysis Provider OracleBio to Showcase Their Xenograft Evaluation Services at the Tumor Models Conference

23 Jul 2013

Product news

OracleBio, providers of high precision digital image analysis services for detailed quantification of histological marker staining within cells and tissues, is pleased to announce it will be a principal sponsor of the forthcoming Tumor Models conference to be held in Boston, MA on the 23-25th July.

At the conference OracleBio’s Chief Scientific Officer, Dr Lorcan Sherry, will also deliver a presentation entitled ‘Detailed Quantification of Drug Response Read-outs in Tumor Xenograft Tissue using Whole Slide Digital Image Analysis’, which will highlight OracleBio’s expertise in using Definiens Tissue Studio™ for quantification of common Xenograft drug efficacy parameters.

Using state of the art Definiens image analysis software, OracleBio can deliver accurate and consistent quantification of histological, IHC and ISH marker staining on a cell-by-cell basis. The company have extensive experience of tumor xenograft analysis, covering a wide range of drug response read-outs including viable and necrotic content, mechanistic markers (proliferation, microvessel density, apoptosis, DNA damage and more) and specific biomarker expression within sub-cellular compartments (nucleus, cytoplasm and membrane).

“Our client base now includes some of the world’s largest pharmaceutical companies,” explains Dr John Waller, COO of OracleBio ”and with over 75 years’ management experience of working within Pharma R&D, biomarker research and image analysis, OracleBio brings a wealth of expertise and value to its customers by combining scientific excellence and Definiens image analysis solutions”.

Dr Sherry continues “Our customers clearly benefit from the high data quality and fast turn-around times we can deliver using Definiens Tissue Studio™, which is considered the industry gold standard image analysis software”.

OracleBio’s success is reflected in a recent expansion of its workforce to include two new business development managers based in the USA and Europe, who aim to enhance the provision of image analysis services within Pharma R&D, diagnostics development, digital pathology and biomarker research.

Tags

Gel Doc / Image AnalysisGel documentation (gel doc) or gel imaging systems are used for the analysis of proteins, antibodies and nucleic acid immobilized in polyacrylamide or agarose gels, membranes or microarrays. Explore a range of a gel imaging systems, densitometers, scanners, transilluminators or UV lamp + CCD cameras for your image analysis solutions. Colorimetric, fluorescent and/or radioisotopic samples can be visualized and documented for further analysis. See gel doc / Image analysis software for quantitative 1D and 2D analysis of your samples. Find the best gel doc / image analysis products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Image AnalysisImage analysis involves the extraction of meaningful information from images, often using software to quantify and interpret visual data. It is widely used in cell biology, material science, and diagnostics. Increasingly, AI is being used to streamline image analysis. Explore image analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.ImmunohistochemistryImmunohistochemistry (IHC) is a technique used to detect specific proteins in tissue samples by using antibodies that bind to target antigens. IHC is widely applied in pathology, immunology, hematology and cancer diagnostics. Explore IHC tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.In Situ Hybridization