GE Healthcare launches Superdex™ 200 Increase

25 Jun 2013

Product news

Superdex™ 200 Increase size exclusion chromatography columns are designed for both preparative and analytical purposes for a broad range of biomolecules, enabling higher purity and improved protein analysis. The columns deliver up to double the resolution or retained resolution in half the time, depending on the conditions selected and the molecule.

Optimised for MAb separation, the Superdex 200 Increase pre-packed columns can be used for small-scale (ug-mg) high resolution gel filtration and for characterizing a variety of different proteins sized between 10,000 – 600,000 Da. The column’s high-flow agarose base matrix is pH stable, easy to clean and with low nonspecific interaction, extending the column’s lifetime.

Superdex 200 Increase, available in three sizes (10/300 GL; 5/150 GL and 3.2/300), can be used with ÄKTA™ chromatography systems, for a variety of applications including protein purification, aggregate analysis, studies of complex formation and screening of samples. All three columns can also be used on a range of HPLC systems.

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Size Exclusion ChromatographySize exclusion chromatography (SEC) is a liquid chromatographic technique used to separate and identify molecules based on their size, including polymers, proteins, nanoparticles & nucleic acid. SEC is further subdivided into gel filtration chromatography (GFC) and gel permeation chromatography (GPC) when an aqueous or organic mobile phase is used respectively. HPLC-based SEC systems and columns are available for analytical separation alongside SEC spin columns or filters to prep samples for many protocols. Find the best size exclusion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
GE Healthcare launches Superdex™ 200 Increase