GE Healthcare Introduces ÄKTA™ avant 150 Liquid Chromatography System for Accelerated Scale-up

GE Healthcare announces the launch of ÄKTA™ avant 150, the second system in the new generation of ÄKTA liquid chromatography systems. ÄKTA avant 150 complements the ÄKTA avant 25 system to fully exploit the advantages of modern BioProcess media, enabling smooth development of scalable chromatographic processes for biopharmaceutical production.

With flow rates up to 150 ml/min, the ÄKTA avant 150 is designed for process development and scale up. The UNICORN™ 6.1 control software enables seamless method transfer between ÄKTA avant 25 and ÄKTA avant 150. UNICORN 6.1 also comes with integrated Design of Experiments (DoE) functionality that provides time and cost savings by capturing the information required for decision making in fewer experiments. ÄKTA avant includes several features for optimal operational security such as a cooled fraction collector and traceable column handling.

ÄKTA avant supports intelligent packing of AxiChrom™ columns for predictable scale up to production scale. The verified, preprogrammed packing methods available ensure optimally-packed beds and decrease operator dependence.

“The ultimate goal is to ensure smooth transition from product discovery to full scale production,” said Nigel Darby, Vice President, Bio-Technologies, GE Healthcare, “ÄKTA avant 150 has been designed for direct scalability using BioProcess media with dedicated column formats. From a production perspective this means cost-effective process development that avoids last-minute surprises.”