Fishing for Genetic Information with Tecan’s HS 4800™ Pro

19 Mar 2009
Emily Marquez-Vega
Publishing / Media

Product news

The high throughput efficiency provided by Tecan’s HS 4800 Pro Hybridization Station is helping researchers at the Pacific Biological Station in British Columbia, Canada, to develop genomics technologies for the management of wild salmon stocks.

Genetic technologies developed by the molecular genetics laboratory are already providing managers with real time information about the timing and distribution of salmon stocks moving through test fishing areas before fisheries are opened. Managers use this information for in-season stock-based management, concentrating fisheries where healthy, abundant stocks are present and implementing conservation strategies for those in need of protection. This same lab is now taking a giant leap forward, providing additional information on the condition of the fish and the likelihood that they will successfully making it to the spawning grounds.

Dr Kristina Miller is head of molecular genetics at the Pacific Biological Station and explained how the Tecan system has advanced the project: “Our aim is to develop tools to assess salmon condition that will allow us to predict physiological and behavioural response to the changing aquatic environment. One of the most important aspects of this work is minimising the technical variation between microarray slides and experiments, and the HS 4800 Pro gives us an exceptionally high consistency rate, as well as a high throughput capacity. The reliability of results is much better than the traditional manual approach and this, combined with the time and money saving aspects, makes the system a clear winner in terms of efficiency.”

To find out more on Tecan’s hybridization stations, follow the company article webpage link on the right hand side of the screen.


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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Fishing for Genetic Information with Tecan’s HS 4800™ Pro