Efficient Handling of DNA Samples with Automatic Capping Solution

5 Jun 2017
Weylan Kiam-Laine
Microbiologist

Product news

Bristol-Myers Squibb (BMS), an American biopharmaceutical company, uses Micronic TPE push caps and electric (de)capping equipment in their lab to make the handling of DNA samples more efficient and less time-consuming. Kelly Shahi, Automation Engineering Specialist at the Automation Research Department commented, “The Micronic automatic capping and decapping solution definitively saves us a lot of time and the headache from capping and decapping all the samples manually.”

BMS has the mission to discover, develop and deliver innovative medicines that help patients to treat serious and life-threatening diseases, in areas such as oncology, cardiovascular disease, immunoscience and fibrosis. Through their Research & Development organization, BMS has built a sustainable pipeline of potential therapies.

Mrs. Shahi works at the BMS R&D facility in Redwood City, California. The goal of this department is to discover biological medicine with a focus on antibodies. Mrs. Shahi noted, “Our main research focus is on discovering and developing fully human antibody-based therapeutics to treat cancer and other life-threatening diseases. Several DNA samples come across the genotyping system in our automation lab for screening. As a result, I do end up storing a lot of samples.” She added, “The samples are stored in case the researchers need to do further screenings down the road. I also go back to pull positive or negative controls for PCR.”

To make the capping and decapping process less time consuming, the R&D department makes use of the Micronic Univo Electric Capper and Decapper. This equipment quickly caps and decaps their tubes with the Micronic TPE push caps. Mrs. Shahi is very satisfied with the Micronic capping solution and would recommend it to other labs: “We just want to be able to handle and store our samples easily and effortlessly. The Micronic solution supports us in this. The capping equipment and TPE push caps have been super-efficient and easy to use, I use them as often as I can. The reliability of the equipment has been great with continuous usage. In addition, the contact with Micronic sales representatives and customer service is also very good.”

The Micronic Univo Electric Capper CP480 can seal an entire rack of 96 tubes within 7 seconds and has a guaranteed evenly capping result. The Electric Capper is compatible with the following push cap formats: TPE Capmats, Capbands, Capclusters and EVA Capmats. The Micronic Univo Electric Decapper DC480 enables significant productivity gains to be made in the opening of multiple sample storage tubes capped with push caps. The DC480 is able to decap 96 tubes in 8 seconds. Through a user friendly interface, it is possible to choose the right rack to decap, without using different adapters.

For further information about Bristol-Myers Squibb please visit https://www.bms.com/. For further information on sample storage solutions please contact Micronic Europe B.V. (Asia, Africa, Europe and Oceania) now at +31-320-277070, Micronic America LLC (North, Central and South America) at +1-484-480-3372 or email to sales@micronic.com.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Labware and Lab SuppliesLabware and lab supplies include various forms of glassware, plasticware, reagents and personal protective equipment (PPE) and are used across all scientific laboratories, enabling daily tasks to be performed. Explore a range of flasks and beakers, petri dishes, carboys and storage bottles. Labware such as condensers, desiccators and burettes are also available for more specific tasks. Find the best labware and lab supplies in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Sample StoragePreserving clinical trial samples to the highest standards is a critical component in maximizing the value of present day and future clinical research. Specialized storage and transportation of these tissue, blood and serum samples reduces the risk of them being damaged or lost.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.Genotyping
Efficient Handling of DNA Samples with Automatic Capping Solution