Contrast in oligonucleotides
2 Jul 2026This resource compares Research Use Only (RUO) and GMP-grade oligonucleotides, highlighting key differences in quality management systems, manufacturing locations, instrumentation, purification methods, production scales, lead times, and intended applications. It shows how RUO oligos are primarily designed for basic research and R&D activities, while GMP-grade oligos are intended to support scale-up, preclinical research, and commercialization.
The resource also outlines the products available in each category, including DNA oligos, RNA oligos, probes, sequencing oligonucleotides, siRNA and miRNA products. Additionally, it details the quality assurance frameworks supporting each offering, including ISO 9001, ISO 13485 and cleanroom manufacturing requirements.
Resource details
- Resource type: Scientific poster
- Page count: 1
- Read time: 2 mins
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Custom GMP-Grade Oligos
MerckIf you commercialize Molecular Diagnostics (MDx), create Laboratory Developed Tests (LDTs), or conduct preclinical research, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards. In the case of oligonucleotide raw materials available with custom specifications, the only option you should consider is Custom GMP-Grade Oligos.