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CHROMABOND<sup>®</sup> HR-XC – the new mixed-mode SPE-phase for basic analytes

MACHEREY-NAGEL GmbH & Co. KG
22 Jun 2008
Greg Smith
Analyst / Analytical Chemist

Product news

MACHEREY-NAGEL the leading European SPE manufacture introduces a new material for solid phase extraction.

This innovative polymer-based strong cation exchanger with remarkable reversed-phase properties is ideal for enrichment of basic compounds. The modern support polymer offers an optimised pore structure and high specific surface. Good reproducibility as well as reliable and cost-efficient analysis are achieved.

The mixed-mode phase allows the possibility for more aggressive washing procedures for matrix removal resulting in cleaner samples and protection of subsequently used HPLC or GC-machines and columns. So quantification of analytes even from heavily contaminated samples can be obtained realising lower limits of detection also for critical matrices like urine or plasma.

CHROMABOND® HR-XC from MACHEREY-NAGEL is the perfect fit for basic analytes in combination with pure PR-phases like CHROMABOND® HR-X.

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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CHROMABOND<sup>®</sup> HR-XC – the new mixed-mode SPE-phase for basic analytes