Chemistry meets the SampleGenie

2 Sept 2007

At the forthcoming ELRIG SBS Meeting at the East Midlands Conference Centre, Nottingham, Genevac has announced that it will show its latest innovative products for rapidly concentrating, drying or lyophilising large samples directly into a small vial.

Visitors to stand 71 will be able to review the recently introduced SampleGenie™ holders which enable large volumes, e.g. pooled HPLC fractions, to be concentrated directly into the vial of the users choice. SampleGenie eliminates a number of handlings stages and can also be used with the Genevac LyoSpeed™ process to concentrate the sample into the vial and then rapidly lyophilise the sample to leave it all in the vial as a dry powder.

Genevac will also show its popular EZ-2 Personal Evaporator system. The EZ-2 now accommodates a wide selection of sample holders enabling evaporation from most common sample container formats including round-bottom flasks up to 500ml, tubes up to 160mm long, custom reaction blocks and shallow or deep-well microplates. To meet the need of the many pharmaceutical and biotech companies switching their compound generation programmes from serial chemistry to parallel synthesis, the EZ-2 is also able to take tubes, flasks and vials directly from the synthesis process, eliminating a manual handling step, increasing recoveries and removing the chance of cross contamination.

Genevac’s knowledgeable applications and sales staff will be available to discuss with customers the best way to meet their requirements for solvent removal. For scientists not able to visit the show please contact Genevac directly.

EZ-2 Series

Genevac

Using the most advanced proven technology in evaporation science, the third generation of the EZ-2 Series has been designed specifically for solvent removal in life science research; be that concentration of samples or complete drying.  The innovative design of the EZ-2 Series presents many advantages for working in parallel within synthesis chemistry, analytical sample preparation and for general-purpose solvent removal needs in life science laboratories. At the heart of the evaporator is a solvent resistant, oil-free vacuum pump, and the high efficiency, defrost-free, SpeedTrap™, which traps all solvents as liquids, even water. Solvents collect in the insulated, plastic coated glass vessel, enabling the user to see the progress of evaporation and determine when the trap should be emptied. The EZ-2 Elite has a special auto-draining collection vessel fitted to the SpeedTrap, which uses the very powerful Scroll pump. The Elite can therefore evaporate the highest boiling solvents such as DMSO and perform the Genevac LyoSpeed fast lyophilisation method for HPLC fractions. There is a low-cost option available on the Standard, Plus and Elite that allows the routine use of hydrochloric acid and aggressive solvents. By building key elements in Hastelloy®, glass or PTFE, full protection against acid chlorides is achieved. New to the HCl Resistance option is the ability to evaporate concentrated nitric acid. This option must be specified when ordering, as it cannot be retrofitted. All EZ-2 models are resistant to routine use of high concentrations of TFA as standard. An additional option is available to allow safe operation for those wishing to use highly explosive solvents, such as pentane or diethyl ether - the inert gas purge system. This system can also be used to preserve oxygen or moisture sensitive samples under an inert gas blanket until the user returns to the evaporator. The EZ-2 Series can also accommodate a wide selection of sample holders, including round-bottom flasks up to 500ml, tubes up to 160mm long (including Dionex ASE® and Radleys Carousel tubes), custom reaction blocks, and shallow or deep-well microtitre plates. EZ-2 Series Models: The Standard (EZ-2) is suitable for water and volatile solvents The Envi (EZ-2 Envi) is recommended for concentration of volatile solvents The Plus (EZ-2 Plus) is recommended for solvents with boiling points upto 165°C The Elite (EZ-2 Elite) is recommended for solvents with boiling points upto 220°C

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Chemistry meets the SampleGenie