Cell Guidance Systems introduces Exo-spin 96 exosome purification kit

Enables rapid purification of exosomes from blood and other samples

9 Nov 2020
Diane Li
Assistant Editor

Product news

Cell Guidance Systems Ltd, a specialist in exosome research reagents and services, has announced the launch of a new product for the purification of exosomes from blood and other samples. The Exo-spin™ 96 exosome purification kit allows researchers to purify exosome samples in the standard 96 well plate format.

The Exo-spin 96 kit is based on the increasingly popular size exclusion chromatography (SEC) method of exosome purification which is now used by most exosome research labs. It is a development of Cell Guidance Systems’ Exo-spin range of SEC single columns, which have been enabling exosome research since 2014, providing a rapid, reliable, and cost-effective way to purify exosomes without specialist equipment.

Exo-spin 96 and Exo-spin mini columns have identical column dimensions and resin bed length, allowing scale up from small to large sample numbers using the same protocol, which takes less than an hour to complete and, in the standard 96-well format, is amenable to automation. Advanced manufacturing techniques and stringent quality control systems used in the production of Exo-spin 96 kits ensure sample-to-sample consistency.

Dr Michael Jones, Cell Guidance System’s CEO, commented: “Exosome research has become increasingly important over the last 10 years. Many projects are scaling up to perform analysis of large sample sets, and exosome researchers therefore need a reliable and cost-effective way of handling these large numbers of samples. This product will enable the generation of higher quality data sets and advance the exosome field.”

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Size Exclusion ChromatographySize exclusion chromatography (SEC) is a liquid chromatographic technique used to separate and identify molecules based on their size, including polymers, proteins, nanoparticles & nucleic acid. SEC is further subdivided into gel filtration chromatography (GFC) and gel permeation chromatography (GPC) when an aqueous or organic mobile phase is used respectively. HPLC-based SEC systems and columns are available for analytical separation alongside SEC spin columns or filters to prep samples for many protocols. Find the best size exclusion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.SECSize exclusion chromatography (SEC) separates molecules based on size, ideal for protein purification, polymer analysis, and biopharma applications. SEC ensures precise characterization of biomolecules for research and industry. Explore peer-reviewed SEC products and compare options for your lab.ExosomesBlood AnalysisThe analysis of blood is vital for many areas of life sciences and forensic investigations. Blood samples can be tested for a number of different reasons such as diagnosis, glucose levels, cholesterol and drug testing.