BioTek's Synergy™ Mx Microplate Reader Receives DLReady™ Certification From Promega Corporation

13 Aug 2009
Sarah Sarah
Marketing / Sales

Product news

BioTek Instruments, Inc., a global leader in the development, manufacture and sale of microplate instrumentation for drug discovery and life science solutions, announces that its Synergy™ Mx Monochromator-based Microplate Reader is now DLReady™ certified for dual-luciferase assays. This certification, awarded by Promega Corporation, establishes the Synergy Mx as meeting the highest performance levels and standards for Promega's Dual-Luciferase® Reporter (DLR™) Assay System - a widely used luminescence-based assay for measuring gene transcription and control in microplate format.

The DLR Assay System provides rapid quantitation of firefly and Renilla luciferase reporters in transfected cells or in cell-free transcription/translation reactions. The combination of two reporter assays in one system provides improved efficiency in less time with attomole sensitivities and no endogenous activity in the experimental host cells.

BioTek's Synergy Mx Monochromator-based Microplate Reader with Ultra Fine-Tuned™ technology provides fluorescence, luminescence and absorbance performance normally only found in dedicated single-mode systems. The top- and bottom-read fluorescence system is fully monochromator-based and equipped with a bandpass selection system for added flexibility. A premium quadruple grating architecture guarantees the best level of wavelength discrimination and smooth spectral scans, and optional dual-reagent dispensers allow precise control of reagent additions and timing in Promega's DLR Assay System as well as kinetic studies, ion channel assays and flash assays. Additionally, a cuvette port increases versatility by allowing for cuvette-based assays and comparisons to standard cuvette spectrophotometers. With its modular format, the required modes can be selected for specific laboratory needs and upgraded at any time as the needs change.

The Synergy Mx joins BioTek's Synergy 2 and Synergy HT Multi-detection Microplate Readers and Synergy 4 Multi-Mode Microplate Reader with Hybrid Technology™; all previously awarded with Promega's DLReady certification.

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MicroplatesMicroplates are multi-well plates used to increase the throughput of biological investigations. The number of wells microplates contain can range from 6 to 3243 wells, with the 96-well format being the most commonly used. Microplates can come tailored for a range of applications including cell culture, PCR, filtration, storage, non-binding surface, protein crystallization, as well as pre-coated, deep well and normal Standard microplates. Additionally, options for microplate colors include clear , black, white or black with clear bottom and white with clear bottom for absorbance microplate reader applications. Find the best microplates for your lab in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.