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Beckman Coulter Introduces Integrated Industrial Robotics Solutions for Drug Discovery

Beckman Coulter Diagnostics
1 Aug 2007

Product news

Beckman Coulter, Inc. announces the availability of integrated Industrial Robotics Solutions for high-throughput pharmaceutical and biotech applications. The Motoman HP3JC Robot provides the transportation foundation for these robust systems. Advanced SAMI® Workstation EX Software provides features tailored to industrial applications while a safety enclosure protects both operator and sample and complies with ANSI/RIA R15.06-1999 standards.

Industrial Robotics Solutions are individually tailored to the application by the Beckman Coulter Integrated Solutions Team, which customizes and optimizes the software along with placement of devices, labware and transport tools. The powerful SAMI EX scheduling software tool facilitates assay design, providing ongoing checks and feedback to the developer, ensuring that the finished method is prevalidated. The software integrates all devices and liquid handlers and interleaves actions and plates for maximum throughput and efficient resource utilization. Tools for 21 CFR Part 11 compliance are also included in SAMI EX.

The Motoman robot arm manufactured by Yaskawa Electric Company has a track record of long MTBF (mean time between failures) in high-workload applications and is the heart of the new Integrated Industrial Solutions. These custom-tailored solutions may incorporate Beckman Coulter liquid handlers, including the Biomek NXP, FXP, BioRAPTR FRD™ and PicoRAPTR™. A wide range of devices and readers can also be integrated into the solution, including Beckman Coulter’s DTX Series Multimode Detectors and new PARADIGM™ Detection Platform.

“A good number of pharmaceutical and biotech customers are graduating from using “islands of automation” to full process automation, which requires the integration of many devices at a high-throughput level,” explained Marc Goldstein, Ph.D., product platform manager for Beckman Coulter. “At the same time there is a higher emphasis on safety. Our new enclosure meets this need, while still providing easy access.”

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Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Integration ServicesIncorporate lab systems, software and equipment with integration services.ADME-ToxicologyADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.

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Beckman Coulter Introduces Integrated Industrial Robotics Solutions for Drug Discovery