Automation of Adherent Cell Culture Maintenance

The demand for mammalian cells in pharmaceutical screening and cell biology research is constantly increasing. Limitations of the currently used cell culture procedures include lack of standardisation associated with poor reproducibility and insufficient throughput.

Hamilton, Life & Brain and University of Bonn have joined their expertise in the development of a system for the automated culture of primary cells, cell lines and embryonic stem cells which provides high quality cells in large numbers. Additionally no increase in spontaneous differentiation compared to the manual control can be observed – a definite indication for the gentle handling of cells by the robot.

With the automation of cell cultures, a significant reduction of manual workload for pharmaceutical and biotech companies comes into reach. The way is now open to further automation of cell lines like CaCo₂ and downstream applications such as reporter gene assays.