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Automated sepsis diagnostic for fast testing in clinical laboratories

Molzym GmbH & Co. KG
8 Dec 2020
Meg Hicks
Student / Graduate

Product news

Molzym, in collaboration with Fraunhofer IZI-BB, have developed a new analytical platform called AutoSepT, which performs fast pathogen identification directly from specimens in less than 5 hours.

Sepsis is a life-threatening disease and its diagnosis requires a fast identification of the infectious pathogen, as every hour without appropriate treatment increases the risk of mortality by up to 7%. Conventional diagnostic procedures such as blood culture are often not fast enough or the culture remains negative due to growth inhibition of the pathogens caused by prior antibiotic administration.

“With AutoSepT, we have developed an innovative walk-away system for the fast and precise culture-independent identification of sepsis-causing pathogens. This new approach offers the opportunity of a fast diagnosis in 4 to 5 hours, in combination with the possibility to identify rare, non-cultivable and inhibited pathogens. Hence, the needs of hospitals and private laboratories for a fast and broad-range solution is met” says project leader Dr. Michael Lustig.

AutoSepT will identify the most frequent sepsis-causing pathogens in just a few hours. In addition, rare and non-cultivable pathogens can be detected based on broad-range 16S Sanger sequencing.

The project is funded by the European Regional Development Fund (ERDF) and the federal state of Brandenburg (ILB).

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Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Pathogen DetectionPathogen detection is the process of identifying harmful microorganisms, including bacteria, viruses, and fungi, that can cause diseases. Accurate pathogen detection is critical for food safety, public health, and clinical diagnostics. Explore pathogen detection products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.SequencingSequencing refers to determining the order of nucleotides in a DNA or RNA molecule. This process is essential in genomics, diagnostics, and evolutionary biology. Techniques like next-generation sequencing (NGS) and Sanger sequencing provide high-throughput and precise data for analyzing genomes and transcriptomes. Browse our peer-reviewed product directory to find the best sequencing tools and reagents, compare products, check reviews, and get pricing directly from manufacturers.SepsisSepsis is a life-threatening response to infection causing organ dysfunction. Research focuses on early detection, biomarkers, and therapies to reduce mortality. Explore tools for sepsis diagnostics and analysis in our peer-reviewed product directory, including detection kits and biomarkers.Bacterial IdentificationInfectious DiseasesInfectious diseases are caused by pathogens such as bacteria, viruses, and fungi. Effective detection, prevention, and treatment are crucial to control outbreaks and improve public health. Diagnostic tools, vaccines, and antimicrobial treatments are essential components of managing these diseases. Research into emerging pathogens and resistance patterns continues to evolve. Browse our peer-reviewed product directory to find the best diagnostic tools, prevention solutions, and treatment options; compare products, read customer reviews, and get pricing directly from manufacturers.

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Automated sepsis diagnostic for fast testing in clinical laboratories