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Automate Your LC/MS Workflow - Bioanalytical STARlet from Hamilton
27 Apr 2016
Lois Manton-O'Byrne, PhD
Executive Editor
Product news
Focused on drugs with a narrow therapeutic range, LC-MS is an increasingly important method for therapeutic drug monitoring (TDM). With numerous variables influencing drug concentration data, sample preparation is key to ensure accuracy of the analytical method. Hamilton’s Bioanalytical STARlet workstation offers fully automated sample preparation for pre-analytical and analytical LCMS workflows including direct injection into the HPLC.
Minimizing human interaction with blood, serum, or plasma samples, the Bioanalytical STARlet includes barcode reading to reduce human errors and provide sample traceability whilst completing just-in-time sample processing during the HPLC runtime.
- Save time and labor with automated QC and calibration curve preparation
- Single sample processing avoids sample degradation
- Direct LC-MS integration for increased walk away time
- Ensure data integrity with complete sample tracking
The Bioanalytical STARlet fully automates all steps for protein precipitation from serum or blood used for therapeutic drug monitoring. The automated process also includes the preparation of the calibration and QC curve. Single sample processing in FlipTubes allows the addition of reagents and the internal standard without sealing or peeling.
The controlled CO-RE Lid Toll transports the FlipTubes from the optional cooled carrier to the high energy shaker, the centrifuge and back to the original position for direct HPLC injection.
An optional dilution step can be performed if it is not possible to inject the high organic solution directly onto the HPLC column.
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