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Anagnostics Partnership Announced for Rapid Identification of Sepsis

Anagnostics Bioanalysis
5 Jul 2012
Sonia Nicholas
Managing Editor and Clinical Lead

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Anagnostics Bioanalysis has announced that it is to enter into a license agreement and partnership with Molzym (Bremen, Germany) to commonly develop hybcell Pathogens DNA, a ground-breaking system for rapidly identifying sepsis causing pathogens out of whole blood.

The deal includes the in-licensing of Molzym’s SepsiTest™ sample preparation kit, which is used for DNA extraction from only a small number of pathogens found in sample material. Together with Anagnostics’ disruptive multiplexed hybcell technology identification of pathogens will be accomplished in less than four hours, improving the prognosis of septic patients significantly.

Early and fast diagnosis of pathogens is crucial for the survival of patients – especially in the initial phase of a developing sepsis. Testing from whole blood overcomes the need for microbiological breeding and reduces time for test results from one or more days down to four hours.

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Hybcell - DNA or protein microarray

Anagnostics Bioanalysis

Anagnostics' hybcell is the world's first DNA or protein microarray based on the use of cylinders instead of slides. hybcell technology is... KINETIC - by means of consecutive scans, FAST - with help of rotational sample agitation, FLEXIBLE - due to fixed starting temperatures, flexible temperature profiles and computer-controlled buffer exchange and EFFICIENT - by automated processing and electronically documenting of up to 96 samples in a single run.

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Hyborg - cylindrical DNA and protein analysis

Anagnostics Bioanalysis

Hyborg is a fully automated device for processing and analysing hybcells (cylindrical DNA and protein microarrays). Hyborg integrates thermocycler, hybridisation station and scanner into a single device. All processing steps - from temperature profiles or exchange of liquids to multi-color scanning - are computer-controlled and documented. Hyborg's concept of totally integrated automation guarantees maximum reproducibility of assays. Autonomous processing of up to 96 hybcells reduces hands-on-time to a minimum and provides maximum ease of use.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.SepsisSepsis is a life-threatening response to infection causing organ dysfunction. Research focuses on early detection, biomarkers, and therapies to reduce mortality. Explore tools for sepsis diagnostics and analysis in our peer-reviewed product directory, including detection kits and biomarkers.

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