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AMSBIO launch new pathogen detection kits

AMSBIO

Several new products have been added by AMSBIO to their growing range of magnetic bead-based nucleic acid extraction kits for pathogen detection

11 Feb 2022
Ellie Abbott
Biochemist

Product news

The MagSi-NA Pathogens MSP (multiple sample pooling) kit sets a new benchmark for automated isolation of nucleic acids (RNA and DNA) from respiratory samples.

Sample pooling is useful in times of high testing and low infection prevalence where traditional sample screening methods are not cost-effective. This will be particularly effective in school and healthcare settings where periodic and comprehensive testing of large numbers of asymptomatic individuals is needed to ensure rapid detection and control of outbreaks. In ‘pooled testing’, samples from many patients are collected and pooled before viral RNA extraction and PCR testing. If pooled samples are determined to be negative, this eliminates the need to test patients individually. Transmission from patients in positive pools can then be prevented through isolation and re-testing. This will allow labs to process more samples while simultaneously reducing reagent costs and saving time.

Traditionally one of the main disadvantages in sample pooling has been the risk of false negative results due to dilution caused by classical sample pooling methods. The MagSi-NA Pathogens MSP kit overcomes this issue by using a non-dilutive technique to sequentially capture all viral RNA present in any of up to six samples, all in a single magnetic bead pellet. Rapid and complete recovery from each sequential sample is ensured by our unique very-high-strength magnetic bead technology. The result is a nearly 6-fold increase in sample throughput and savings of up to 80% on extraction and PCR reagent costs. This is achieved without any reduction in sensitivity or increase in false negative rates.

AMSBIO’s new rQ MagSi-NA Pathogens kit provides an elegant solution for the automated isolation of nucleic acids (RNA and DNA) from a wide range of samples using magnetic particle processors. The automation-ready rQ MagSi-NA Pathogens kit, consisting of conveniently pre-filled deep-well plates, will also help labs increase throughput and allow for the preparation of up to 96 samples in less than 20 min. The pre-filled plates can be used directly in PurePrep 96, 32, 16 or KingFisher automated, nucleic acid purification systems for the extraction of pathogenic DNA and RNA to reduce hands-on time and minimises errors to achieve consistent and reproducible results.

In addition, AMSBIO has introduced a CE-IVD marked version of the existing popular Mag-Si NA pathogens kit. The new MagSi-DX Pathogens kit has been specifically validated for SARS-CoV-2 diagnostic workflow and is ideal for labs requiring CE-IVD products for use in human diagnostics. CE-IVD marked versions of MagSi-NA Pathogens MSP and rQ MagSi-NA Pathogens are scheduled for release in the coming months.

All these new kits are based on AMSBIO’s market-leading MagSi-Na Pathogens kit which uses strong magnetic beads to allow fast magnetic separation even from viscous human respiratory swabs and saliva samples to achieve consistently high yields of viral RNA, ideal for use in SARS-CoV-2 diagnostics.

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PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Respiratory InfectionsRespiratory infections are caused by pathogens such as bacteria, viruses, and fungi, leading to diseases like pneumonia, tuberculosis, and COVID-19. It is important to identify respiratory infections quickly in patients to ensure appropriate treatment and care, and to prevent sepsis. Browse our peer-reviewed product directory to find the best tools for respiratory infection detection, compare products, check reviews, and get pricing directly from manufacturers.Pathogen DetectionPathogen detection is the process of identifying harmful microorganisms, including bacteria, viruses, and fungi, that can cause diseases. Accurate pathogen detection is critical for food safety, public health, and clinical diagnostics. Explore pathogen detection products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.In Vitro DiagnosticsIn vitro diagnostics (IVD) involve testing samples outside the body, typically in a laboratory, to diagnose diseases or conditions. IVD technologies include blood tests, molecular assays, and other bodily fluid tests, enabling accurate diagnosis and monitoring of diseases. These tests are essential for guiding treatment decisions in clinical settings. Browse our peer-reviewed product directory to find the best IVD solutions; compare products, check reviews, and get pricing directly from manufacturers.Molecular DiagnosticsMolecular diagnostics use an individual’s genetic code and gene expression to diagnose and monitor diseases. The technique is used increasingly in the field of infectious diseases and oncology, as well as areas such as coagulation, HLA typing and pharmacogenomics. Molecular diagnostics plays a pivotal role in personalized medicine.Infectious DiseasesInfectious diseases are caused by pathogens such as bacteria, viruses, and fungi. Effective detection, prevention, and treatment are crucial to control outbreaks and improve public health. Diagnostic tools, vaccines, and antimicrobial treatments are essential components of managing these diseases. Research into emerging pathogens and resistance patterns continues to evolve. Browse our peer-reviewed product directory to find the best diagnostic tools, prevention solutions, and treatment options; compare products, read customer reviews, and get pricing directly from manufacturers.

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AMSBIO launch new pathogen detection kits