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Advances in HPLC/UHPLC Technology & Method Development Webinar Series

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In this series of free webinars, discover the latest techniques and technologies helping to push the limits of chromatography

26 Jul 2021
Finn Price
Administrator / Office Personnel

Expert insights

In this series of free webinars, explore the latest advances in HPLC/UHPLC technology and method development. Discover the new techniques and technologies helping researchers simplify the analysis of polar compounds, automate process monitoring in pharmaceutical and biopharmaceutical production, optimize oligonucleotide analysis, and much more.

Register by clicking on the live events below to hear from analytical science and separations experts. Ask the speakers your questions in the live Q&A sessions following each presentation. Plus, check out a selection of our on-demand webinars and download related resources to supplement your own research.

Automated process monitoring via liquid chromatography (LC)

Monday, August 16, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

In this webinar, Dr. Daniel Kutscher, from Agilent Technologies, will present a newly developed online LC platform, which provides automated sample analysis via direct injections or retained samples from flow reactors, batch reactors, upstream bioreactors, and downstream purification devices.

Register here

Easy, rapid and direct analysis of challenging polar compounds

Wednesday, August 18, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Connor Flannery, from Restek, will introduce a simpler approach to the retention and separation of these challenging compounds — a unique stationary phase specifically designed to selectively retain polar analytes. Flannery will highlight specific application examples that will illustrate the rapid and direct analysis of underivatized amino acids, ultrashort-chain PFASs, glyphosate, and other polar contaminants.

Register here

LC/MS to reveal the hidden post-translational modifications in neurodegeneration

Available to view on demand

Dr. Blaine Roberts, from Emory University, discusses the application of quantitative proteomics to a large set (~2,000 samples) of cerebral spinal fluid (CSF) samples to better understand the role of acute-phase proteins in Alzheimer’s disease. Roberts will also talk through a rapid 10-minute triple quad mass spectrometer method with heavy-labeled peptides that can provide in-depth information about the amount of targeted proteins in human CSF. Register to discover how the implementation of quantitative mass spectrometry and ion mobility reveal hidden biology and improve our understanding of a complex disease.

Watch on demand

The power of (U)HPLC selectivity for diverse pharmaceutical methods

Available to view on demand

With so much attention paid over the years to column efficiency, it is important not to forget about the power of selectivity. In this webinar, Dr. Jason Anspach will cover the basics of chromatographic selectivity and provide you with a template to help you decide between fully porous or core-shell particles to get the most out of your pharmaceutical separations.

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Optimize IP-RP method development for oligonucleotide analysis

Available to view on demand

Ensuring high-quality oligonucleotides for therapeutic applications relies on robust analytical methods. In this webinar, hear from principal scientist Dr. Brook Koshel as she discusses method development considerations when selecting an appropriate ion-pairing agent. She also shares tips and tricks for developing efficient methods for ion-pair reversed-phase (IP-RP) analysis of oligonucleotides.

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Improving the sensitivity of LC-MS methods for characterization and quantitation of synthetic oligonucleotides

Available to view on demand

Join Brian Rivera, from Phenomenex, as he discusses how LC-MS sensitivity can be increased by mobile phase optimization and column selection. He also demonstrates how to minimize adduct formation and enhance ionization efficiency, which can in turn increase MS sensitivity for improved characterization and quantitation data.

Watch on demand

Oh no! Not another boring webinar on column lifetime?

Available to view on demand

Are you looking for a comprehensive summary on how to protect your HPLC column from early failure, clogging and performance loss? Join Andreas Borowiak, from Agilent Technologies, to learn what the typical lifetime for an HPLC column should be, how to identify the root cause of early column failure, how to protect your column from solvent contaminations, and how to properly clean and store your HPLC columns.

Watch on demand

Discover more free resources here:

  • Advances in HPLC Special Feature: Learn about the latest HPLC systems, read interviews with leading scientists and download new resources to support your method development. Visit special feature >>
  • How to Buy HPLC Technology: In this free HPLC buying guide, discover the key factors and application considerations when looking to buy new columns. Plus, read impartial reviews to gain insights from industry-leading professionals. Download eBook >>
  • How to Buy LC-MS Technology for Life Sciences: In this free LC-MS buying guide, discover the key factors and application considerations when looking to buy LC-MS technology, from sample prep to the latest LC-MS system. Plus, read impartial reviews to gain insights from your peers around the world. Download eBook >>
  • Analysis of pesticides in cannabis products: In this video on The Scientists' Channel, Dr. Nathaly Reyes Garcés explains a simple workflow for the accurate analysis of pesticides in cannabis products via solvent extraction and GC analysis. Colton Myers discusses his work analyzing terpenes in cannabis through headspace analysis, and Ashlee Gerardi outlines the focus for Restek and how its team can help with bespoke cannabis testing workflows and method development, in the face of ongoing changes within the industry. Watch here>>
  • Liquid chromatography - Tips, tricks & guidance: In this eBook, we look at Agilent Technologies’ products portfolio to help you navigate the increasingly complex landscape of LC. Discover how transformative Agilent’s InfinityLab LC/MSDiQ and Poroshell 120 columns could be to your LC workflow. Download eBook >>

Register for the Advances in HPLC/UHPLC Technology & Method Development Webinar Series here>>

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. HPLC Method DevelopmentIt is important to develop and validate HPLC methods in order to identify, quantify or purify compounds of interest in the most efficient way. Effective method development ensures optimization, quality control and cost effectiveness.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.HPLCHigh-performance liquid chromatography (HPLC) is a technique for separating, identifying, and quantifying components in mixtures. It is widely used in chemical, pharmaceutical, and environmental analysis to ensure purity and identify unknown compounds. Explore the best HPLC systems in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers.LC-MSLiquid Chromatography-Mass Spectrometry (LCMS) is a powerful analytical technique that combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. It is widely used for qualitative and quantitative analysis of complex mixtures in pharmaceuticals, proteomics, and environmental studies. Browse our peer-reviewed product directory to find the best LCMS systems, compare products, check reviews, and get pricing directly from manufacturers.

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