A Novel Dynamic Delivery System Enabling High Efficiency Transfection of Cells
9 Oct 2013
This poster evaluates the TransIT-X2™ Dynamic Delivery System, a novel, non-liposomal polymeric delivery system designed to facilitate high efficiency and functional delivery of plasmid DNA and/or siRNA. An extensive head-to head comparison with a popular liposomal reagent is described and functional co-delivery of plasmid DNA and siRNA and functional delivery of siRNA and miRNA are assessed to demonstrate dual abilities of this system.
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TransIT-X2™ Dynamic Delivery System
Mirus Bio LLCAn innovative, polymeric system for efficient delivery of plasmid DNA and siRNA/miRNA. Experience the transfection breakthrough. Achieve superior transfections with an innovative polymeric system that efficiently delivers both DNA and RNA out of the endosome and into the cytoplasm overcoming a critical barrier to nucleic acid delivery.Head-to-head comparisons against the Lipofectamine® 2000 illustrate superior or equal luciferase expression using TransIT-X2 in 26 of 30 cell types; 11 cell types had expression levels 2-fold higher than Lipofectamine 2000.TransIT-X2™ Dynamic Delivery System Features: Efficiency - Exceptional Broad Spectrum Transfection Versatility - Cutting Edge Delivery of Plasmid DNA and siRNA Technology - Novel, Non-Liposomal, Polymeric Delivery