A Comprehensive Toolkit for Exosome Research

4 Apr 2018
Han Yin
Administrator / Office Personnel

Product news

AMSBIO has announced that its exosome product range now includes everything you need for studying and using exosomes, from isolation and characterization, to cargo profiling and engineering, and more.

Exosomes are small membrane vesicles with a size ranging from 40 to 100 nm. They are known to serve as functional mediators in cell interaction leading to cancer metastasis. Metastasis is a complex multistep process of cancer cell invasion, survival in blood vessels, attachment to and colonization of the host organ. Exosomes influence every step of this cascade and therefore represent a novel strategy for cancer therapy. For high-quality exosome isolation – AMSBIO offer the ExoQuick family of reagents for ultracentrifugation-free isolation, ExoMAX Opti Enhancer to provide a rapid, easy way to prepare samples for density gradient-based exosome isolation, or Exo-FLOW products for IP- and FACS-based exosome isolation. In addition, AMSBIO offers a range of products that easily detect the presence of exosomes with general and tissue-specific antibodies and arrays, as well as flow cytometry reagents that label exosomes.

When you need to quantify the exosomes you’ve isolated, AMSBIO offers a range of options that meet most needs. For the fastest and most sensitive antibody-based quantitation, the ExoELISA™-ULTRA CD63 kit provides outstanding sensitivity down to 1-200 µg protein equivalent—and a fast, 4-hour workflow. If you want even faster quantitation (20 minutes) that does not rely on antibody binding, the EXOCET™ kit provides direct measurement of the activity of a known exosomal protein, Acetylcholinesterase (AChE). FluoroCet is a more sensitive version of EXOCET that relies upon fluorescence-based quantitation.

Tracking exosomes and their cargo is made easily using AMSBIO Exosome labels that include ready-to-go Cyto-tracers, ExoGlow reagents, and XPACK lentivectors. If you are interested in characterizing exosomal RNA or proteins for biomarker profiling, AMSBIO also offers a range of intuitive, easy-to-use products. When you are ready to move from studying exosomes to using them as research tools, AMSBIO offers a complete suite of products for exosome engineering.

Do you use exosome products from AMSBIO in your laboratory? Write a review today for your chance to win $400 Amazon voucher.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Sample HandlingProper and careful handling of samples is important in scientific studies to ensure the integrity of specimens. This will prevent deterioration and cross contamination, and improve the accuracy of sample tracking procedures.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.ExomesSample ProcessingSample processing is required to prepare samples prior to analysis. Technologies used for sample processing include homogenizers, grinders, mills and mixers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.
A Comprehensive Toolkit for Exosome Research