Miniaturized High Throughput Kinase Screening Using the Echo® Liquid Handler and Access™ Workstation
29 Jan 2015Small molecule screening against kinases is commonly used to discover drug candidates that target various human diseases. By combining the nanoliter-scale and non-contact Labcyte Echo 525 liquid handler with the robust and ultra-sensitive Promega ADP-Glo assay, high throughput screening can be improved. This poster demonstrates the reproducibility of inhibition and IC50 determinations from a high throughput screen performed with the Echo 525 liquid handler.
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Echo® 525 Liquid Handler
Beckman Coulter Life SciencesThe Echo 525 platform, like the other Echo liquid handler models, is designed to use sound energy to transfer reagents. Unlike the other Echo models, the Echo 525 platform transfers at a larger volume increment (25 nL). This enables the more rapid transfer of aqueous reagents required in biochemical and genomics assays setup.