Measuring subvisible particles and aggregates using FlowCam LO

17 Mar 2022

In this application note, Yokogawa Fluid Imaging Technologies uses the FlowCam LO to directly compare the particle size distributions of aqueous samples containing Polystyrene Latex calibration beads, ETFE particles, and IgG aggregates obtained from both LO and FIM analyses.

FlowCam LO

Yokogawa Fluid Imaging Technologies, Inc

Innovative particle characterization with FlowCam® LO combines flow imaging microscopy (FIM) and light obscuration (LO) into a single analytical solution. Beyond the compendial light obscuration method to fulfill USP <787> and <788> requirements, flow imaging microscopy provides an orthogonal method for quality control of subvisible particulate matter.

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Measuring subvisible particles and aggregates using FlowCam LO