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Application Note: Lowering Detection Limits for 1,4-Dioxane in Drinking Water Using Large Volume Injection in an Unmodified Splitless GC Inlet
17 April 2013

This application note describes a method for the analysis of 1,4-dioxane in drinking water using an unmodified split/splitless inlet with concurrent solvent recondensation–large volume splitless injection (CSR-LVSI) to lower reporting limits without concentrating the extract. SPE is performed using Resprep® SPE cartridge from Restek for EPA method 522 then analysis by GC-MS. This CSR-LVSI technique improves detectability with no specialized equipment or changes to standard laboratory instrumentation.