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Future-proofing the Biopharmaceutical QC Laboratory: Using the ACQUITY UPLC H-Class Bio System to Run SEC-HPLC and SEC-UPLC

10 Aug 2014

In this application note, Waters demonstrate that legacy SEC-HPLC methods can be easily transferred to the ACQUITY UPLC H-Class Bio System without any modification to existing method details. With adjustments to flow rate and run time based on changes in particle size and column dimensions, SEC-UPLC can easily be performed with the same ACQUITY UPLC H-Class Bio System without any consequence to protein quantification requirements.

ACQUITY UPLC H-Class PLUS Bio System

Waters

The ACQUITY UPLC H-Class PLUS Bio System delivers the benefits of UPLC's resolution, sensitivity, and throughput in a system purpose-built for the analysis of proteins, peptides, nucleic acids, and glycans.

(7)

Empower™ Chromatography Data System

Waters

The Empower Chromatography Data System is Waters’ compliance-ready chromatography data software (CDS) for advanced data acquisition, processing, and reporting that simplifies the management of chromatography test results.

(25)

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Future-proofing the Biopharmaceutical QC Laboratory: Using the ACQUITY UPLC H-Class Bio System to Run SEC-HPLC and SEC-UPLC