Application Note: Confocal Imaging with Improved Signal-to-Noise Ratio and Superresolution
17 January 2018

Confocal imaging has grown to become the standard choice for most fluorescence microscopy applications. The optical sectioning ability of a confocal imaging system has been brought about by placing a field stop, the pinhole. This application note looks into the details of the recent development and market introduction of the Airyscan detector from ZEISS. Where traditional pinhole and detector design have been reworked to offer greatly improved resolution and signal-to-noise ratio (SNR).