Application Note: Aggregate analyses by light scattering – Complementary and orthogonal
19 May 2021

Biotherapeutic regulatory filingsrequire detailed characterization of degradation pathways including aggregation. Learn how three orthogonal light scattering techniques complement each other to analyze and quantify soluble and sub-micron insoluble aggregates. This poster describes the capabilities of SEC-MALS, FFF-MALS and CG-MALS and how they work together to provide a comprehensive picture of irreversible and reversible aggregates.