Application Note: Structure-based drug discovery with cryo-EM
8 October 2019
Cryo-electron microscopy (cryo-EM) is a powerful biophysical technique that allows researchers to visualize molecular assemblies at near-atomic resolution. In this application-based eBook, we outline the application of cryo-EM in structure-based drug discovery and look at how state-of-the-art microscopes, such as the Krios G4 cryo-TEM from Thermo Fisher Scientific, help to keep leaders in the pharmaceutical industry at the forefront of drug discovery.
Download this eBook to learn more about:
- The single-particle analysis (SPA) workflow
- Micro-electron diffraction (microED) using nanocrystals
- The applications of cryo-EM in structure-based drug design
- Scientists who are using this technique, including Nobel laureate Dr. Richard Henderson