Accelerating Science: How to cure the incurable with cell and gene therapy

Application Note: Rabbit monoclonal antibody development from ProSci
7 December 2023

Recombinant rabbit monoclonal antibodies are excellent tools for challenging targets such as small molecules or post-translational modifications. They have high affinity due to the rabbit’s robust immune system. Several methods are used to develop custom rabbit monoclonal antibodies, such as hybridoma generation, phage display, or B-cell cloning. This application note highlights ProSci’s B-cell development platform that allows for careful selection of the ideal antibodies and preservation and immortalization through conversion to a recombinant. The note also explores ProSci’s rabbit monoclonal antibody development service that offers two different packages: Premier – Client-provided splenocytes and Pro – Client-provided antigens, as well as customized packages.