ResourceLife Sciences
Nanoscopy meets Lifetime: Introducing τ-STED
19 Sept 2021Fluorescence lifetime provides a new perspective for STED nanoscopy. With the unique τ-STED functionality from Leica Microsystems, your scientific research will benefit from super-resolution STED offering excellent performance with a much lower light dose and getting rid of undesired background signal. τ-STED combines the optical signals from STED and the photophysical information from the fluorescence lifetime at unprecedented speeds. This new approach to STED uses phasor analysis in a novel way. τ-STED enables an increased STED resolution and elimination of uncorrelated background noise, even at low excitation and STED powers.
In this application note, find out how you can use τ-STED to perform:
- STED imaging at cutting-edge resolution with dramatically lower excitation and STED light dose
- Gentle live-cell STED imaging for extended time-lapse experiments
- Multicolor applications with the best STED probes
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Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FluorescenceThe emission of fluorescence occurs when a photon of energy is supplied to a fluorescent chemical compound by an external source, causing it to become excited. Fluorescence can be detected and measured for different purposes using microplate readers, fluorescence microscopes, fluorescence scanners, and flow cytometers.Fluorescence MicroscopyFluorescence microscopy has become an essential tool in biology, as well as in materials science. The application of many fluorochromes has made it possible to identify cells and sub-microscopic cellular components with a high degree of specificity. Using multiple fluorescence labels, different probes can simultaneously identify several target molecules.ImagingImaging techniques are essential for obtaining visual representations of samples to understand structures, processes, and function in biological, chemical, and physical research. These tools range from traditional light microscopy to advanced imaging modalities like MRI and electron microscopy, providing researchers with valuable data for diagnostics, drug discovery, and material analysis. Explore imaging solutions in our peer-reviewed product directory to compare products, check reviews, and get pricing directly from manufacturers.
