Application Note: ISO 8871-3 - Measuring Particle Release from Stoppers with Hound
3 September 2018
Detection of fibers and other particulate contamination on rubber stoppers used in pharmaceutical manufacturing follow the ISO 8871-3 guidelines. Parental rejection rate is directly related to the number of particle contaminants on the rubber stopper. This application notes highlight how the number and size of particles on a rubber stopper can quickly be determined by Hound using microscopy, Raman or Laser-Induced Breakdown Spectroscopy.